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Statement [Line Items]
Statement [Line Items]
Summary Of Operating Lease Presentation In Consolidated Statements Of Operations [Table Text Block]
Summary Of Operating Lease Presentation In Consolidated Statements Of Operations [Table Text Block]
Summary of Operating Lease Presentation in Consolidated Statements of Operations
Cybersecurity Risk Board of Directors Oversight [Text Block]
Accounts receivable
Increase (Decrease) in Accounts Receivable
Plan Name
Plan Name [Domain]
Preferred Stock Convertible Conversion Price
Preferred Stock, Convertible, Conversion Price
Entity Address, Postal Zip Code
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Remaining performance obligations
Revenue, Remaining Performance Obligation, Amount
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Entity Incorporation, State or Country Code
Acquisition-related costs
Business Combination, Acquisition Related Costs
Revenues [Abstract]
Revenue:
Number of operating segments
Number of Operating Segments
Amount Receivable Upon Achievement Of Regulatory And Commercial Milestones
Amount receivable upon achievement of regulatory and commercial milestones.
Amount receivable upon achievement of regulatory and commercial milestones
Acquisition of ZebiAI
Business Combination Disclosure [Text Block]
Weighted Average Exercise Price Per Share, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Beginning balance, shares
Ending balance, shares
Shares, Outstanding
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Summary of Net Assets Acquired Based on Estimated Fair Values
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
Number of shares, released
Share based compensation arrangement by share based payment award RSUs released in period gross.
Share based compensation arrangement by share based payment award RSUs released in period gross.
Auditor Name
Level 2 [Member]
Fair Value, Inputs, Level 2 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Operating Income (Loss) [Member]
Operating Income (Loss) [Member]
Investment, Affiliated Issuer [Member]
Investment, Affiliated Issuer [Member]
Cowen [Member]
Cowen.
Investments:
Investments, Fair Value Disclosure [Abstract]
Business Combination, Consideration Transferred, Total
Consideration transferred
Business Combination, Consideration Transferred
Number of shares that would be issued upon milestone achievement
Number of Shares Would Be Issued Upon Milestone Achievements
Number of Shares Would Be Issued Upon Milestone Achievements
Issuance of common stock in initial public offering, net.
Issuance of common stock in initial public offering, net
Issuance of common stock in initial public offering/follow-on offering, net
Investments, Total
Investments
Investments
Property and Equipment [Member]
Property and Equipment.
Description of income tax examinations
Income Tax Examination, Description
Lessee, Operating Leases [Text Block]
Operating Leases
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
T D Securities [Member]
TD securities.
TD Securities [Member]
Stock issued during period value acquisition new issues.
Stock Issued During Period Value Acquisition New Issues
Issuance of common stock in follow-on offering, net
Product and Service
Product and Service [Axis]
Common stock issued upon milestone achievement.
Common stock issued upon milestone achievement
Intangible asset
Indefinite-Lived Intangible Assets (Excluding Goodwill)
Indefinite-Lived Intangible Assets (Excluding Goodwill), Ending Balance
Indefinite-Lived Intangible Assets (Excluding Goodwill), Beginning Balance
Indefinite-Lived Intangible Assets (Excluding Goodwill), Total
Milestone payments
Milestone Payments
Milestone payments.
Commitments And Contingencies Disclosure [Table]
Commitments And Contingencies Disclosure [Table]
Commitments and contingencies disclosure.
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Time-Based Stock Options [Member]
Time-based stock options.
Cybersecurity Risk Management Processes Integrated [Text Block]
Common Stock
Equity [Text Block]
Operating lease liabilities
Operating Lease Liabilities [Member]
Operating lease liabilities.
Schedule of Operating Leases Presentation in Consolidated Balance Sheets
Schedule Of Operating Lease Presentation In Consolidated Balance Sheet Table [Text Block]
Schedule of operating lease presentation in consolidated balance sheet.
Periodic Change in Additions of Property And Equipment Within Current Liabilities
Periodic change in additions of property and equipment within current liabilities.
Periodic change in additions of property and equipment within current liabilities
Sale of Stock [Domain]
Cash and Cash Equivalents
Cash and Cash Equivalents [Domain]
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Available-for-sale Debt Securities in an Unrealized Loss Position
Milestone Payment Due Upon Specified Regulatory Milestone Achievement For Each Target Thereafter
Milestone payment due upon specified regulatory milestone achievement for each target thereafter.
Milestone payment due for each target thereafter
Entity Central Index Key
Summary Of The Restricted Stock Activity
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
CARES Act description of corporate tax payers.
C A R E S Act Description Of Corporate Tax Payers
CARES Act, description of corporate tax payers
Percentage of commission owed to sales agent under at-the-market offering.
Percentage of commission owed to sales agent under at-the-market offering
Percentage of commission owed to sales agent under at-the-market offering
Debt Securities, Available-for-Sale, Unrealized Loss Position [Abstract]
Periodic Change in Costs to Obtain License Agreement Within Current Liabilities
Periodic change in costs to obtain license agreement within current liabilities.
Periodic change in costs to obtain license agreement within current liabilities
Number of shares, cancelled
Cancelled, Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Auditor Opinion [Text Block]
Changes in assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Amount of increase (decrease) in the fair value of contingent consideration recognized in the income statement.
Change in fair value of contingent consideration liabilities
Change in fair value of contingent consideration liability
Underwriting discounts, commissions and other offering expenses.
Underwriting Discounts, Commissions And Other Offering Expenses
Underwriting discounts, commissions and other offering expenses
CARES Act, percentage of eliminates of taxable income
CARES Act Perecentage Of Taxable Income Limitation
CARES Act perecentage of taxable income limitation.
Common Stock, Shares, Issued, Total
Common stock shares issued
Common Stock, Shares, Issued
Investments with a maturity of one year or less [Member]
Investments With Maturity Of One Year Or Less [Member]
Investments with maturity of one year or less.
CARES Act, percentage of bonus depreciation
C A R E S Act Percentage Of Bonus Depreciation
CARES Act, percentage of bonus depreciation.
Risk-free interest rate minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Nature of Business and Basis of Presentation
Business Description and Basis of Presentation [Text Block]
Preferred Stock [Member]
Income Statement [Abstract]
Entity Address, State or Province
Issuance of common stock via employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
After-tax contributions
Current Assets.
Current Assets [Member]
Current Assets [Member]
Shares authorized additionally under ESPP
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Debt Securities, Available-for-Sale, Unrealized Loss Position
Total, Fair Value
Total, Fair Value
Amount Receivable in Achievement of Regulatory and Commercial Milestones
Amount Receivable in Achievement of Regulatory and Commercial Milestones
Amount receivable in achievement of regulatory and commercial milestones
Aggregate Intrinsic Value, Vested Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Milestone payments
Business combination contingent consideration liability contingent milestone payments
Business combination contingent consideration liability contingent milestone payments.
Milestone payment Due
Milestone Payment Due Upon Specified Regulatory Milestone Achievement
Milestone payment due upon specified regulatory milestone achievement.
Cover [Abstract]
Comprehensive Loss
Comprehensive Income, Policy [Policy Text Block]
Net loss per share, basic
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss attributable to common stockholders per share, basic
Milestone payments completion period
Milestone Payments Completion Period
Milestone payments completion period.
Accrued compensation costs.
Accrued Compensation Costs
Compensation costs
Contract with Customer, Asset, after Allowance for Credit Loss, Total
Contract asset
Contract with Customer, Asset, after Allowance for Credit Loss
Payment for upfront consideration.
Payment For Upfront Consideration
Payment for upfront consideration
Proceeds From Issuance Of Common Stock Through Exercise Of Stock Options
Proceeds from issuance of common stock through exercise of stock options.
Proceeds from issuance of common stock through exercise of stock options
Unrealized Losses
Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Operating expenses:
Operating Expenses [Abstract]
Issuance of common stock upon acquisition of ZebiAI, shares
Stock Issued During Period, Shares, Acquisitions
Milestone Payments [Member]
Milestone payments.
Agreement renewal period
Research And Development Arrangement Contract To Perform For Others Renewal Period
Research and development arrangement contract to perform for others renewal period.
Document Annual Report
Consolidation Items [Domain]
Number Of New Genetic Disease Programs
Number of new genetic disease programs.
Number of genetic disease programs
Transfer of Active Pharmaceutical Ingredient [Member]
Transfer Of Active Pharmaceutical Ingredient.
Transfer of Active Pharmaceutical Ingredient [Member]
Stock-based compensation expense
Total share-based compensation expense
Share-Based Payment Arrangement, Expense
Issuance of common stock in initial public offering shares.
Issuance of Common Stock in Initial Public Offering Shares
Issuance of common stock in initial public offering/follow-on offering, net, Shares
Deferred tax assets:
Deferred Tax Assets, Net [Abstract]
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Plan Name
Plan Name [Axis]
Segment Reporting [Abstract]
Options and Warrants Outstanding, Number of Shares Beginning Balance
Options and Warrants Outstanding, Number of Shares Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Current assets:
Assets, Current [Abstract]
Operating lease assets
Deferred Tax Liabilities Operating Lease Assets
Deferred tax liabilities operating lease assets.
Accrued expenses text block.
Accrued Expenses [Text Block]
Accrued Expenses
Transfer of License and Related Know-how.
Transfer of License and Related Know-How [Member]
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Weighted Average Grant Date Fair Value, Cancelled
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Product and Service
Product and Service [Domain]
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive loss
Accumulated other comprehensive loss
Term of the lease
Lessee, Operating Lease, Term of Contract
Investments with a maturity of one to two years [Member]
Investments With Maturity Of One To Two Years [Member]
Investments with maturity of one to two years.
Operating Leased Assets [Line Items]
Operating Leased Assets [Line Items]
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Total property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Lessee, Operating Lease, Liability, to be Paid, Year Four
2028
Investments
Investment, Policy [Policy Text Block]
Cash flows from operating activities:
Net Cash Provided by (Used in) Operating Activities [Abstract]
Fair value on a recurring basis [Member]
Fair Value, Recurring [Member]
Other Income and Expenses [Abstract]
Other income:
Summary of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis and Level of the Fair Value Hierarchy
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Tax Cuts and Jobs Act of 2017, description of corporate tax payers
Tax Cuts And Jobs Act Of2017 Description Of Corporate Tax Payers
Tax Cuts and Jobs Act of 2017, description of corporate tax payers.
Common stock par value
Common Stock, Par or Stated Value Per Share
Options outstanding to purchase common stock [Member]
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List]
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Vesting of restricted common stock ,shares
Vesting Of Restricted Common Stock Shares
Vesting of restricted common stock shares.
Statement of Cash Flows [Abstract]
Counterparty Name
Counterparty Name [Axis]
Antidilutive Securities, Name [Domain]
Intangibles
Deferred Tax Assets, Goodwill and Intangible Assets
Other
Deferred Tax Assets, Other
Equity Components
Equity Components [Axis]
Entity Address, Address Line One
Collaboration agreement transaction price
Collaborations agreement transaction price
Collaborations agreement transaction price.
Sharebased Compensations Arrangement by Share Based Payments Award Options Non Vested Intrinsic Value 1
Sharebased compensations arrangement by share based payments award options non vested intrinsic value.
Aggregate Intrinsic Value, Unvested Value
Summary of Computation of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Number of Shares Underlying RSUs, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Computer Equipment [Member]
Computer Equipment [Member]
Issuance of common stock upon milestone achievement, shares.
Issuance of common stock upon milestone achievement, shares
Issuance of common stock upon milestone achievement,shares
Research and Development Expense [Abstract]
Research and development expenses
Subsequent Event Type
Subsequent Event Type [Axis]
Summary of Antidilutive Securities Excluded From Computation of Earnings Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Number of common stock issued upon milestone achievements.
Number of Common Stock Issued Upon Milestone Achievements
Number of common stock issued upon milestone achievement
Patent Costs
Patent Costs Policy [Text Block]
Patent costs.
Shares - Beginning
Shares - Ending
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
R&D credit carryovers
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Entity Voluntary Filers
BMR Hampshire, LLC [Member]
BMR-Hampshire, LLC. [Member]
BMR-Hampshire, LLC. [Member]
Operating lease assets and liabilities, net
Increase decrease in operating lease assets and liabilities net
Increase decrease in operating lease assets and liabilities net.
Amendment Flag
Stock compensation
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Percent
Directors and Officers.
Directors and Officers [Member]
Additional shares issued
Stock issued during period additional shares issued
Stock issued during period additional shares issued.
DE Shaw Research [Member]
D E Shaw Research [Member]
DE shaw research.
Orphan drug tax credits, begin to expire year
Deferred Tax Assets Tax Credits Orphan Drug Begin to Expire Year.
Deferred tax assets tax credits orphan drug begin to expire year.
Non-current operating lease liabilities
Operating lease liabilities, net of current portion
Operating Lease, Liability, Noncurrent
Aggregate gross proceeds from the sale of shares
Sale of Stock, Consideration Received Per Transaction
Federal [Member]
Domestic Tax Jurisdiction [Member]
Text Block [Abstract]
Milestone payment due upon specified regulatory milestone achievement for first three targets.
Milestone Payment Due Upon Specified Regulatory Milestone Achievement for First Three Targets
Milestone payment due for first three targets
Offering price per share
Sale of Stock, Price Per Share
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Net loss
Net loss
Number of shares exercised
Issuance of common stock through exercise of stock options, shares
Exercised, Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Shares, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Research and development expenses [Member]
Research and Development Expense [Member]
Research and Development Expenses
Percentage of additional common stock authorized
Percentage Of Additional Common Stock Authorized
Percentage of additional common stock authorized.
Follow on offering.
Follow-On Offering [Member]
Follow-On Offering [Member]
Elevar Therapeutics, Inc.
Elevar [Member]
Elevar Therapeutics, Inc. [Member]
Loss on sale of equipment
Loss on sale of equipment
Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property
Equity Component
Equity Component [Domain]
Statistical Measurement
Statistical Measurement [Domain]
Cash received up on conditions satisfied
Contract With Customer Cash Received
Contract with customer cash received.
Document Financial Statement Error Correction [Flag]
General and Administrative Expense, Total
General and administrative expenses
General and Administrative Expenses
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds from sale of equipment
Proceeds from Sale of Property, Plant, and Equipment
Total other income, net
Other Nonoperating Income (Expense)
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Furniture and Fixtures [Member]
Furniture and Fixtures [Member]
Transfer of License [Member]
License And Transfer Agreement [Member]
License and transfer agreement.
Cybersecurity Risk Management Processes Integrated [Flag]
Description of Income tax benefit, likelihood of realized upon ultimate settlement
Income Tax Examination, Likelihood of Unfavorable Settlement
Deferred revenue
Deferred Revenue, Current
Deferred Revenue, Current, Total
Preferred Stock, Shares Issued, Total
Preferred stock shares issued
Preferred Stock, Shares Issued
Fixed lease payments
Operating lease, payments
Operating Lease, Payments
Retirement Benefits
Retirement Benefits [Text Block]
Business combination, contingent milestone payments.
Business Combination, Contingent Milestone Payments
Contingent Milestone Payments
Shares, Unvested
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Payables and Accruals [Abstract]
RLY-2139 and Estrogen Receptor Alpha Degrader [Member]
RLY-2139 and Estrogen Receptor Alpha Degrader [Member]
RLY-2139 and Estrogen Receptor Alpha Degrader [Member]
Rule 10b5 Arr Modified Flag.
Rule 10b 5 Arr Modified Flag
Rule 10b5-1 Arrangement Modified
Number of New Novel Programs
Number of New Novel Programs
Number of novel programs
Issuance of common stock via employee stock purchase plan, shares
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Shares of common stock purchased
Consolidation Items [Axis]
Risk-free interest rate maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Industry Sector [Axis]
Weighted Average Exercise Price Per Share, Cancelled
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Restricted cash
Restricted Cash, Noncurrent
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Class of Stock
Class of Stock [Domain]
Payments to be received upon achievement of other specified development commercialization and sales based milestones does not exercise option to participate in collaboration
Payments To Be Received Upon Achievement Of Other Specified Development Commercialization And Sales Based Milestones Does Not Exercise Option To Participate In Collaboration
Payments to be received upon achievement of other specified development commercialization and sales based milestones does not exercise option To participate in collaboration
Other Comprehensive Income (Loss), Net of Tax
Total other comprehensive (loss) income
Deferred Tax Assets Tax Credits Research and Development Begin to Expire Year
Deferred tax assets tax credits research and development begin to expire year.
Research and development tax credits, begin to expire year
Collaborative Arrangement Disclosure [Text Block]
Collaboration and License Agreements
Total comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock shares outstanding
Common Stock, Shares, Outstanding
Schedule Of Changes In Fair Value Of Contingent Consideration Liability [Table Text Block]
Schedule of changes in fair value of contingent consideration liability.
Schedule of Changes in Contingent Consideration Liability
Payments to Acquire Investments, Total
Purchases of investments
Payments to Acquire Investments
License Agreement Transaction Price
License agreement aransaction price.
License agreement transaction price
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Contingent Consideration by Type [Axis]
Preferred stock par value
Preferred Stock, Par or Stated Value Per Share
ZebiAI Therapeutics, Inc.
ZebiAI Therapeutics, Inc. [Member]
Zebi A I Therapeutics Inc [Member]
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.
Antidilutive Securities [Axis]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Schedule of Restricted Stock Units Activity
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Entity Interactive Data Current
Issued shares of common stock
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares
Contract Assets and Liabilities
Contract Assets and Liabilities Policy [Policy Text Block]
Contract assets and liabilities.
Two Thousand Twenty Four Sales Agreement [Member]
Two thousand twenty four sales agreement.
2024 Sales Agreement [Member]
Transfer of Active Pharmaceutical Ingredients [Member]
Transfer Of Active Pharmaceutical Ingredients [Member]
Transfer of active pharmaceutical ingredients.
Weighted Average Grant Date Fair Value, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Related Party Transaction
Related Party Transaction [Domain]
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash, cash equivalents, and restricted cash per statements of cash flows
License Agreement Terms [Member]
License Agreement Terms [Member]
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Statement of Financial Position Location, Balance [Axis]
Statistical Measurement
Statistical Measurement [Axis]
Recently Issued Accounting Pronouncements Not Yet Adopted
Description Of New Accounting Pronouncements Not Yet Adopted Policy [Text Block]
Description of new accounting pronouncements not yet adopted.
Operating lease costs
Operating Lease, Cost
Total assets
Assets, Fair Value Disclosure
At-the-Market Offerings [Member]
At-the-Market Offerings.
At-the-Market Offerings [Member]
Milestones repayable current.
Milestones Repayable Current
Milestones repayable (Note 11)
Summary of Future Minimum Lease Payments
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Weighted Average Grant Date Fair Value, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Total unrecognized compensation cost related to the unvested stock awards, Weighted average period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Net deferred tax assets
Deferred Tax Assets, Net
Research and Development Costs
Research and Development Expense, Policy [Policy Text Block]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense
Income Statement Location
Statement of Income Location, Balance [Axis]
Cash and Cash Equivalents
Cash and Cash Equivalents [Axis]
Shares held
Investment Owned, Balance, Shares
Total assets
Assets
Expected term from grant through exercise
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Deferred Tax Liabilities, Gross, Total
Deferred Tax Liabilities, Gross
Total deferred tax liabilities
Number of RSUs, vested
Number of Shares Underlying RSUs, Vested
Number of Shares Underlying RSUs, Vested
Shares - Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Business Acquisition [Line Items]
Recently Adopted Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Entity Address, City or Town
Accumulated Other Comprehensive Income (Loss) [Member]
AOCI Attributable to Parent [Member]
Proceeds from issuance of common stock through follow-on offering, net
Proceeds from issuance of common stock through follow-on offering, net
Proceeds from issuance of common stock through follow-on offering, net.
Auditor Location
Assets
Assets, Fair Value Disclosure [Abstract]
Undesignated Preferred Stock [Member]
Undesignated preferred stock.
UndesignatedPreferredStock [Member]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Number of RSUs, cancelled
Number of Shares Underlying RSUs, Cancelled
Cancelled
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table]
399 Binney Street [Member]
399 Binney Street, Cambridge, Massachusetts.
Binney Street, Cambridge, Massachusetts [Member]
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Schedule of Total Stock Compensation Expense Recognized
Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items]
Depreciation, Total
Depreciation expense
Depreciation
Restricted Cash And Cash Equivalents At Carrying Value [Abstract]
Restricted cash and cash equivalents at carrying value abstract.
Grant date share price
Share Price
Fair value of shares, vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value
Schedule of Segment Reporting Information, by Segment [Table]
Current Liabilities [Member]
Current liabilities.
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Private Placement [Member]
Private Placement [Member]
Stock Compensation
Share-Based Payment Arrangement [Text Block]
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Construction in Process [Member]
Construction in Progress [Member]
Significant Accounting Policies [Line Items]
Significant Accounting Policies [Line Items]
Significant accounting policies.
Share-based Payment Award, Number of Shares Authorized
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Common stock shares issued upon conversion.
Common stock shares issued upon conversion
Outstanding convertible preferred stock converted into common shares
Series A Preferred Stock [Member]
Series A Preferred Stock [Member]
Weighted-average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Fair Value Disclosures [Abstract]
Research and Manufacturing Contracts
Research And Manufacturing Contracts Policy [Text Block]
Research and manufacturing contracts.
Other segment expenses.
Other Segment Expenses [Abstract]
Other segment expenses (income)
Entity Public Float
CARES Act, percentage of corporate charitable deduction limit
C A R E S Act Percentage Of Corporate Charitable Deduction Limit
CARES Act, percentage of corporate charitable deduction limit.
Stock Issued During Period, Value, New Issues
Issuance of common stock, net
Deferred Tax Assets, Net of Valuation Allowance
Net deferred tax assets
Issuance of common stock through exercise of stock options
Stock Issued During Period, Value, Stock Options Exercised
Current liabilities:
Liabilities, Current [Abstract]
Number Of Shares Granted
Number of shares granted.
Number of shares granted
Total liabilities
Nonfinancial Liabilities Fair Value Disclosure
Document Type
Number of discovery stage programs
Number of discovery stage programs.
U.S agency securities [Member]
US Government Agencies Debt Securities [Member]
U.S. agency securities [Member]
Issuance of common stock upon milestone achievement.
Issuance of common stock upon milestone achievement
Issuance of common stock upon milestone achievement
Weighted average number of shares outstanding diluted.
Weighted Average Number Of Shares Outstanding Diluted
Weighted average shares of common stock, diluted
Title of 12(b) Security
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Weighted Average Remaining Contractual Life, Unvested
Share Based Compensation Arrangement By Share Based Payment Award Options Non Vested Weighted Average Remaining Contractual Term
Share based compensation arrangement by share based payment award options non vested weighted average remaining contractual term.
Statement of Financial Position Location, Balance [Domain]
Lessee, Operating Lease, Liability, to be Paid, Year Five
2029
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Statement of Stockholders' Equity [Abstract]
Net operating loss carryback period
C A R E S Act net operating losses carry back period
CARES Act net operating losses carry back period.
Document Fiscal Period Focus
Total intrinsic value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Research and Development Expense, Total
Research and development expense
Research and development expenses
Research and Development Expense
Granted, Number of Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of stock options granted
Acquisition date
Business Acquisition, Effective Date of Acquisition
Asset Class [Domain]
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Property and equipment
Property, Plant and Equipment, Gross
Research and development arrangement, annual fee
Research And Development Arrangement Annual Fee
Research and development arrangement, annual fee.
Elevar Agreement [Member]
Elevar agreement.
Subsequent Event Type
Subsequent Event Type [Domain]
Cash And Cash Equivalents Fair Value Disclosure [Abstract]
Cash equivalents:
Cash and cash equivalents fair value disclosure.
Increase in valuation allowance
Increase In Deferred Tax Assets Valuation Allowance
Increase in deferred tax assets valuation allowance.
Lessee, Leases [Policy Text Block]
Leases
Schedule of Estimated Fair Value of Stock Options
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Operating lease assets
Operating Lease Assets [Member]
Operating lease assets.
Operating Segment
Operating Segments [Member]
Average share value of 5-day
Business Acquisition, Share Price
Debt securities in continuous unrealized loss position for more than 12 months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
12 Months or Longer, Fair Value
Financial Instruments
Financial Instruments [Domain]
ZebiAI.
ZebiAI [Member]
Industry Sector [Domain]
Operating lease agreement expiration date
Lease Expiration Month And Year
Lease expiration month and year.
Research and development tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Research and Development
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research and development tax credit carryforwards.
Sale of Stock [Axis]
Cash flows from investing activities:
Net Cash Provided by (Used in) Investing Activities [Abstract]
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Lease liability
Deferred Tax Assets Lease Liability
Deferred tax assets lease liability.
Net operating loss carryforwards, not subject to expiration
Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Collaboration revenue
Revenue from Contract with Customer, Excluding Assessed Tax
License and other revenue
Concentration of Credit Risk and Significant Suppliers
Concentration Of Credit Risk And Significant Suppliers Policy [Text Block]
Concentration of credit risk and significant suppliers.
Income Taxes
Income Tax Disclosure [Text Block]
Market-Based Awards [Member]
Market-based awards.
Market-Based Awards Member
Summary of Reconciliation of Expected Income Tax (Benefit) Computed Using Federal Statutory Income Tax Rate to Effective Income Tax Rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Investment, Issuer Affiliation [Axis]
Vesting of restricted stock units, Shares.
Vesting of restricted stock units, Shares
Credit Facility
Credit Facility [Domain]
Research and development arrangement, term of contract
Research And Development Arrangement Term Of Contract
Research and development arrangement, term of contract.
Collaboration And License Arrangement [Line Items]
Collaboration And License Arrangement [Line Items]
Collaboration and license arrangement.
Debt Securities Available For Sale [Table]
Debt Securities, Available-for-Sale [Table]
Deferred Tax Liabilities, Net [Abstract]
Deferred tax liabilities
Entity Address, Address Line Two
Liabilities and Stockholders' Equity
Liabilities and Equity [Abstract]
Document Period End Date
Segment, Reconciliation of Other Items from Segments to Consolidated [Abstract]
Reconciliation to consolidated net loss:
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities
ICFR Auditor Attestation Flag
Total
Effective Income Tax Rate Reconciliation, Percent
Stockholders' Equity Note [Abstract]
Proceeds From Issuance Of Common Stock Through Private Placement Net
Proceeds from issuance of common stock through Private Placement, net.
Proceeds from issuance of common stock through Private Placement, net
Proceeds from Sale and Maturity of Other Investments, Total
Proceeds from Sale and Maturity of Other Investments
Proceeds from maturities and sales of investments
Net operating loss carryforwards, state
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
Vesting of restricted common stock
Vesting Of Restricted Common Stock Value
Vesting of restricted common stock value.
Anti-dilutive effect
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Stand-alone selling prices.
Standalone Selling Prices ("SSP") [Member]
Standalone Selling Prices [Member]
Stand-alone Selling Prices ("SSP") [Member]
Accrued expenses and other current liabilities.
Accrued Expenses And Other Current Liabilities
Total accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Accrued External Research And Development Expense Current
Accrued external research and development expense current.
External research and development costs
Stock compensation expense
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Accrued expenses
Accrued expenses and other current liabilities
Accrued Liabilities, Current
Total accrued expenses
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Other expenses
Other Research and Development Expense
Exercise price of stock options
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Exercise Price
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Segment reporting, CODM, profit (loss) measure, how used, description
Income Tax Expense (Benefit), Total
Income tax benefits
Income Tax Expense (Benefit)
Basis of presentation
Basis Of Presentation Policy [Text Block]
Basis of presentation.
Components of Deferred Tax Assets [Abstract]
Trading Symbol
Business Combinations [Abstract]
Total stockholders' equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Schedule of Investments [Abstract]
Document Financial Statement Restatement Recovery Analysis [Flag]
Deferred Tax Assets Operating Loss Carryforwards Begin To Expire Year
Deferred tax assets operating loss carryforwards begin to expire year.
Net operating loss carryforwards, begin to expire year
Deferred Tax Assets, Gross
Total gross deferred tax assets
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment and Tax
Unrealized holding (loss) gain
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Other liabilities
Other Liabilities, Noncurrent
Other Liabilities, Noncurrent, Total
Unvested and outstanding restricted stock units [Member]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs) [Member]
Related Party Transactions [Abstract]
Increase (Decrease) in Deferred Revenue
Deferred revenue
Cybersecurity Risk Management, Strategy, and Governance [Table]
Land subject to ground leases
Land Subject to Ground Leases
Total unrecognized compensation cost related to the unvested stock awards, Value
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Dividend upon extinguishment of preferred stock.
Extinguisment upon modification of Series C Preferred Stock (Note 9)
Dividend upon extinguishment of Series C Preferred Stock (Note 9)
Dividend upon extinguishment of Series C Preferred Stock
ESPP [Member]
Employee Stock Purchase Plan [Member]
Employee stock purchase plan.
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Schedule of Total Stock Compensation Expense Recognized
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Employer matching contribution
Defined Contribution Plan, Employer Discretionary Contribution Amount
Geographical
Geographical [Axis]
Unrealized Losses
Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Leases [Abstract]
Maturity days for highly liquid investments
Cash And Cash Equivalents Maturity Date Description
Cash and cash equivalents maturity date description.
Area of land
Area of Land
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Research and Development Services [Member]
Research and development services.
Research and Development Services [Member]
Collaboration and License Agreement [Member]
Collaborative Arrangement [Member]
Additional payments to be received upon achievement of other specified development commercialization and sales based milestones does not exercise option to participate in collaboration
Additional Payments To Be Received Upon Achievement Of Other Specified Development Commercialization And Sales Based Milestones Does Not Exercise Option To Participate In Collaboration
Additional payments to be received upon achievement of other specified development commercialization and sales based milestones does not exercise option to participate in collaboration.
Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
CARES Act, percentage of eliminates of taxable income
C A R E S Act Percentage Of Eliminates Of Taxable Income
CARES Act, percentage of eliminates of taxable income.
Conversion of convertible preferred stock into common stock upon initial public offering
Stock Issued During Period, Value, Conversion of Convertible Securities
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List]
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Schedule of Business Acquisitions, by Acquisition [Table]
Expected volatility rate minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Share based compensation unrecognized compensation expected recognition term
Share based Compensation Unrecognized Compensation Expected Recognition Term
Share based compensation unrecognized compensation expected recognition term.
Scenario [Axis]
Dividend yield rate
Dividend yield
Expected dividend yield
Security Exchange Name
Summary of Fair Value of Available-for-Sale Investments by Type of Security
Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]
Contingent Earnout Payments related to acquisition of ZebiAI
Business combination contingent consideration arrangements change in amount of contingent earnout payments
Business combination contingent consideration arrangements change in amount of contingent earnout payments.
Change in carrying value of Contingent Earnout Payments
Counterparty Name
Counterparty Name [Domain]
Dividends, Common Stock, Total
Dividends declared
Dividends, Common Stock
Deferred Tax Assets, Tax Credit Carryforwards, Total
Tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards
Business Acquisition, Acquiree [Domain]
Total operating expenses
Operating Expenses
Segment net loss
Aggregate Intrinsic Value, Unvested Value
Share based Compensation Arrangement by Share Based Payment Award Options Non Vested Intrinsic Value 1
Share based compensation arrangement by share based payment award options non vested intrinsic value.
RSU granted
Share Based Compensation Arrangement By Share Based Payment Award R S Us Grants In Period Gross
Share based compensation arrangement by share based payment award RSUs grants in period gross.
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Class of Stock
Class of Stock [Axis]
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Less: accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Payment related to collaboration or other agreements
Payment Related To Collaboration Or Other Agreements
Payment related to collaboration or other agreements.
Contribution toward the cost of construction and tenant improvements for the premises
Contribution toward the cost of construction and tenant improvements for the premises
Contribution toward the cost of construction and tenant improvements for the premises.
Fair Value Disclosures [Text Block]
Fair Value Measurements
Milestones paid
Milestones Paid
Milestones paid.
Lessee, Operating Lease, Liability, to be Paid, Year Three
2027
Weighted average grant date fair value of stock option granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Subsequent Event [Member]
Subsequent Event [Member]
Maximum [Member]
Maximum [Member]
Total liabilities and stockholders' equity
Liabilities and Equity
Right of use asset
Operating lease assets
Operating Lease, Right-of-Use Asset
Prepaid Expense, Current
Prepaid Expense, Current, Total
Prepaid expenses
Prepaid balance
Number of shares, vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure of non-cash activities:
Laboratory Equipment [Member]
Laboratory Equipment [Member]
Laboratory equipment.
Retirement Benefits [Abstract]
Investments
Investment [Text Block]
Net loss per share, diluted
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss attributable to common stockholders per share, diluted
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Income tax disclosure.
Liabilities assumed in asset acquisition
Liabilities assumed in asset acquisition
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities, Total
Total liabilities
Liabilities
Common Stock, Voting Rights
Common Stock, Voting Rights
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Total current assets
Assets, Current
Net cash provided by (used in) investing activities
Net Cash Provided by (Used in) Investing Activities
Forecast [Member]
Forecast [Member]
Common stock shares sold
Stock Issued During Period, Shares, New Issues
Issuance of common stock, net, shares
Business Combination Contingent Consideration Liability Contingent Milestones Payments
Business combination contingent consideration liability contingent milestones payments.
Business combination contingent consideration liability contingent milestones payments
Unrecognized Tax Benefits, Ending Balance
Unrecognized Tax Benefits, Beginning Balance
Unrecognized tax benefits
Unrecognized Tax Benefits
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Unvested
Weighted Average Exercise Price Per Share, Unvested
Number of shares, released
Share Based Compensations Arrangements By Share Based Payment Award R S Us Released In Period Gross
Share based compensations arrangements by share based payment award RSUs released in period gross.
Investment, Issuer Affiliation [Domain]
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Operating lease option to extent
Lessee, Operating Lease, Existence of Option to Extend [true false]
Entity Filer Category
Percentage of payment related to collaboration or other agreements
Percentage Of Payment Related To Collaboration Or Other Agreements
Percentage of payment related to collaboration or other agreements.
Time-Based R S U's.
Time-Based RSUs [Member]
Time-Based RSUs [Member]
Summary of Reserved Shares of Common Stock
Reserved Shares Of Common Stock For Future Issuance Table Table [Text Block]
Tabular disclosure of reserved shares of common stock for future issuance.
Business combination consideration transferred equity interests issued.
Business combination consideration transferred equity interests issued
Aggregate fair value consideration transferred
Development milestone payments
Development Milestone Payments
Development milestone payments.
Contractual term of stock options
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Contractual Term
Share-based compensation arrangement by share-based payment award, fair value assumptions, contractual term.
Current Fiscal Year End Date
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Property and Equipment
Property, Plant and Equipment, Policy [Policy Text Block]
Less: interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Lease Agreement
Lease Agreement [Member]
Lease Agreement [Member]
Stock compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Payment For Transfer Of Active Pharmaceutical Ingredient
Payment for transfer of active pharmaceutical ingredient.
Payment for transfer active pharmaceutical ingredient and other material
Related Party Transaction
Related Party Transaction [Axis]
Aggregate Intrinsic Value, Outstanding Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
precision oncology and genetic disease indications.
Precision Oncology And Genetic Disease Indications [Member]
Precision Oncology and Genetic Disease Indications [Member]
Operating lease option to terminate
Lessee, Operating Lease, Existence of Option to Terminate [true false]
Entity Registrant Name
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss
Total, Unrealized Losses
Total, Unrealized Losses
Total, Unrealized Losses
Proceeds From Issuance Of Common Stock Via At The Market Offerings Net
Proceeds from issuance of common stock via at the market offerings net.
Proceeds from issuance of common stock via at-the-market offerings, net
Beginning balance
Fair value of contingent milestone payments and earnout payments
Contingent consideration liability
Ending balance
Business Combination, Contingent Consideration, Liability
Business Combination, Contingent Consideration, Liability, Total
Commissions and other offering expenses
Commissions And Other Offering Expenses
Commissions and other offering expenses.
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Net Loss Per Share
Earnings Per Share [Text Block]
Letter of credit expiration date
Letter of credit expiry date
Debt Instrument, Maturity Date
Entity Emerging Growth Company
Money market funds [Member]
Money Market Funds [Member]
Other Liabilities, Current
Other current liabilities
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted average shares of common stock, basic
Investments [Abstract]
Operating lease liabilities, net of current portion
Operating Lease Liabilities Net Of Current Portion [Member]
Operating lease liabilities net of current portion.
Non Rule 10b51 Arr Modified Flag.
Non Rule 10b51 Arr Modified Flag
Non-Rule 10b5-1 Arrangement Modified
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
Expected volatility rate maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Common stock shares authorized
Common Stock, Shares Authorized
CARES Act, period of qualified improvement property for cost-recovery
C A R E S Act Period Of Qualified Improvement Property For Cost Recovery
CARES Act, Period of qualified improvement property for cost-recovery.
Property and equipment, useful life
Property, Plant and Equipment, Useful Life
Net proceeds
Proceeds from issuance of common stock upon exercise of stock options
Proceeds from Issuance of Common Stock
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Accounts payable and accrued expenses
Increase (Decrease) in Accounts Payable and Accrued Liabilities, Total
Increase (Decrease) in Accounts Payable and Accrued Expenses
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Weighted Average Exercise Price Per Share, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Financial Instrument
Financial Instrument [Axis]
Weighted Average Remaining Contractual Life, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Net Loss Per Common Share
Earnings Per Share, Policy [Policy Text Block]
General and administrative expenses [Member]
General and Administrative Expense [Member]
Impairment, Long-Lived Asset, Held-for-Use, Total
Impairment loss of long lived assets
Impairment, Long-Lived Asset, Held-for-Use
Revenue Recognition
Revenue [Policy Text Block]
Share-Based Payment Arrangement [Abstract]
Impairment of Long-Lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Average stock price upon milestone settlement.
Average stock price upon milestone settlement
Average stock price upon milestone settlement
Other Income Expense
Other income (expense).
Other income (expense)
Other income (expense)
Other (income) expense
Hampshire street, Cambridge, Massachusetts> [Member]
Hampshire Street, Cambridge, Massachusetts [Member]
60 Hampshire Street [Member]
Issuance of common stock upon acquisition of ZebiAI
Stock Issued During Period, Value, Acquisitions
Cybersecurity Risk Role of Management [Text Block]
Debt Securities, Available-for-sale, Total
Fair Value
Debt Securities, Available-for-Sale
Accounting Policies [Abstract]
Series C Preferred Stock [Member]
Series C Preferred Stock [Member]
Schedule of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Nature of Business and Basis of Presentation [Line Items]
Nature Of Business And Basis Of Presentation [Line Items]
Nature of business and basis of presentation.
Schedule Of Operating Leased Assets [Table]
Schedule of Operating Leased Assets [Table]
Income Tax Disclosure [Abstract]
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Number of milestone targets
Number Of Milestone Targets
Number of milestone targets.
Maximum additional amount received upon milestone achievement
Maximum Additional Amount Received Upon Milestone Achievement
Maximum additional amount received upon milestone achievement.
Interest income
Interest Income, Other
Interest income
Restricted Cash
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Statement [Table]
Statement [Table]
External Costs for Programs in Clinical Trials
External costs for programs in clinical trials.
External costs for programs in clinical trials
Segment Reporting [Policy Text Block]
Segments
Schedule of Property and Equipment, Net
Property, Plant and Equipment [Table Text Block]
HR+/HER2- breast cancer.
H R H E R 2 Breast Cancer [Member]
HR+/HER2- Breast Cancer [Member]
Deferred Tax Assets, Tax Credit Carryforwards, Orphan Drug
Deferred tax assets, tax credit carryforwards, orphan drug.
Orphan drug tax credit carryforwards
Requisite service period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Requisite Service Period
Preferred stock shares authorized
Preferred Stock, Shares Authorized
Securities Act File Number
Entity File Number
Segment Information
Segment Reporting Disclosure [Text Block]
Net decrease in cash, cash equivalents, and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Adjustments or reconciling items
Adjustments or reconciling items.
Earnings Per Share [Abstract]
Professional services
Accrued Professional Services Current
Accrued professional services current.
Cash equivalents [Member]
Cash Equivalents [Member]
Gain (Loss) on Sale of Investments
Gain (Loss) on Sale of Investments, Total
Realized gain on sale of investments
Net realized gain on sale of investments
Stock compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
State taxes, net of federal benefit
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Statement of Financial Position [Abstract]
Loss from operations
Operating Income (Loss)
Segment net loss
Historical volatility rate
Expected volatility
Volatility
Schedule of Estimated Fair Value of Employee Stock Purchase Plan
Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
Letter of Credit [Member]
Letter of Credit [Member]
Entity Shell Company
Entity Tax Identification Number
Assets
Assets [Abstract]
Significant Accounting Policies [Table]
Significant Accounting Policies [Table]
Significant accounting policies.
Entity Current Reporting Status
Weighted Average Remaining Contractual Life, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Proceeds from issuance of common stock via employee stock purchase plan
Proceeds From Issuance Of Common Stock Via Employee Stock Purchase Plan
Proceeds from issuance of common stock via employee stock purchase plan.
Non-refundable payments
Non-Refundable Payments
Non-refundable payments.
Proceeds from issuance of convertible preferred stock, net of issuance costs
Proceeds from Issuance of Convertible Preferred Stock
Common stock issued upon milestone achievement [Member]
Common Stock Issued Upon Milestone Achievement [Member]
Common stock issued upon milestone achievement.
Subsequent Events [Abstract]
Assets obtained in asset acquisition
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets, Total
Geographical
Geographical [Domain]
Document Fiscal Year Focus
Permanent differences
Effective Income Tax Rate Reconciliation Permanent Differences
Effective income tax rate reconciliation permanent differences.
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Undesignated preferred stock, $0.001 par value, 10,000,000 shares authorized as of December 31, 2024 and December 31, 2023; no shares issued and outstanding as of December 31, 2024 and December 31, 2023
Business Combination, Description [Abstract]
Business Acquisition [Axis]
Weighted Average Sales Price Per Share
Weighted average sales price per share.
Weighted-average sales price of shares issued
City Area Code
Letter of credit
Letters of Credit Outstanding, Amount
Total current liabilities
Liabilities, Current
Common Stock Restriction Period
Common stock, restriction period.
Common stock restriction period
Laboratory and Computer Equipment [Member]
Laboratory and computer equipment.
Laboratory and Computer Equipment [Member]
Income tax computed at federal statutory rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Other Third Parties [Member]
Other Third Parties [Member]
Other third parties [member].
Conversion of convertible preferred stock into common stock upon initial public offering, shares
Stock Issued During Period, Shares, Conversion of Convertible Securities
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Local Phone Number
Additional Payment Included in Revenue Upon Achievement Of Other Specified Development Commercialization And Sales Based Milestones Does Not Exercise Option To Participate In Collaboration
Additional Payment Included in Revenue Upon Achievement Of Other Specified Development Commercialization And Sales Based Milestones Does Not Exercise Option To Participate In Collaboration
Additional payment included in revenue upon achievement of other specified development commercialization and sales based milestones does not exercise option to participate in collaboration
Contingent Earnout Payments
Business combination contingent consideration liability, contingent earnout payments
Business combination contingent consideration liability, contingent earnout payments
Business combination contingent consideration liability, contingent earnout payments.
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock shares outstanding
Preferred Stock, Shares Outstanding
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Employee Related Expenses
Employee related expenses.
Employee related expenses
Additional Paid in Capital, Ending Balance
Additional Paid in Capital, Beginning Balance
Additional Paid in Capital, Total
Additional paid-in capital
Additional Paid in Capital
Intangible asset
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles
Genentech Agreement [Member]
Genentech Agreement [Member]
Genentech agreement.
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Less than 12 Months, Unrealized Losses
Less than 12 Months, Unrealized Losses
Income Tax Authority
Income Tax Jurisdiction [Axis]
Income Taxes
Income Tax, Policy [Policy Text Block]
Commitments and Contingencies Disclosure [Abstract]
Investments [Member]
Investments [Member]
Schedule of Held-to-Maturity Securities [Line Items]
Schedule of Held-to-maturity Securities [Line Items]
Convertible Preferred Stock [Member]
Convertible Preferred Stock [Member]
Earnout Payments [Member]
Earnout payments.
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Summary of Deferred Tax Assets and Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Research And Development Arrangement Expiration Date
Research and development arrangement, expiration date.
Initial research and development arrangement, expiration date
Operating lease liabilities, current
Operating Lease, Liability, Current
Operating lease liabilities
Collaboration And License Arrangement [Table]
Collaboration And License Arrangement [Table]
Collaboration and license arrangement.
Segment Net Income (Loss)
Segment net income (loss).
Segment net loss
Income Tax Authority
Income Tax Jurisdiction [Domain]
Accumulated Deficit [Member]
Retained Earnings [Member]
Contingent consideration payment description
Business Combination, Contingent Consideration Arrangements, Description
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Document Transition Report
Increase in number of shares of common stock available for issuance
Increase in Common Stock Capital Shares Reserved For Future Issuance
Increase in common stock capital shares reserved for future issuance.
Percentage of fair market value of common stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Lessee, Operating Lease, Liability, to be Paid, Year Two
2026
Postemployment Benefits [Abstract]
Antidilutive Security, Excluded EPS Calculation [Table]
Proceeds from issuance of common stock under ESPP
Proceeds from Stock Plans
Weighted Average Exercise Price Per Share, Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Auditor Firm ID
Minimum [Member]
Minimum [Member]
Common Stock [Member]
Common Stock [Member]
Restricted Cash, Total
Restricted cash
Restricted Cash
Milestone payment due upon specified regulatory milestone achievement for each target after first three.
Milestone Payment Due Upon Specified Regulatory Milestone Achievement For Each Target After First Three
Milestone payment due for each target after first three target
Weighted Average Exercise Price Per Share, Unvested
Weighted Average Grant Date Fair Value, Ending Balance
Weighted Average Grant Date Fair Value, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Entity Well-known Seasoned Issuer
Nature Of Business And Basis Of Presentation [Table]
Nature Of Business And Basis Of Presentation [Table]
Nature of business and basis of presentation.
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Other comprehensive (loss) income:
Income Statement Location
Statement of Income Location, Balance [Domain]
Lessee, Operating Lease, Liability, to be Paid, Year One
2025
Increase (Decrease) in Other Operating Liabilities
Increase (Decrease) in Other Operating Liabilities, Total
Other liabilities
Collaboration And License Arrangement [Abstract]
Collaboration and license arrangement.
Unrealized (loss) gain on investments
Debt Securities, Available-for-Sale, Unrealized Gain (Loss), Total
Debt Securities, Available-for-Sale, Unrealized Gain (Loss)
Commitments and Contingencies Disclosure [Line Items]
Commitments And Contingencies Disclosure [Line Items]
Commitments and contingencies disclosure.
Other Assets, Current
Other current assets
Entity Common Stock, Shares Outstanding
2021 Sales Agreement [Member]
Two Thousand Twenty One Sales Agreement [Member]
Two thousand twenty one sales agreement.
Number of shares that would be issued upon milestone achievement
Number of Shares Would Be Issued Upon Milestone Achievement
Number of shares would be issued upon milestone achievement.
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Less than 12 Months, Fair Value
Net operating loss carryforwards, subject to expiration
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration
Loss on initial consolidation of VIE
Loss on initial consolidation of VIE
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Assets Loss On Initial Consolidation Of Variable Interest Entity
Business combination recognized identifiable assets acquired and liabilities assumed assets loss on initial consolidation of variable interest entity.
2016 Plan [Member]
Two Thousand Sixteen Plan
Two Thousand Sixteen Plan [Member]
2016 Plan [Member]
CARES Act maximum percentage of interest deducted by tax payers.
C A R E S Act Maximum Percentage Of Interest Deducted By Tax Payers
CARES Act, maximum percentage of interest deducted by tax payers
Unrecognized compensation related to unvested market-based awards
Unrecognized Compensation Related To Non Vested Awards Granted
Unrecognized compensation related to non vested awards granted.
Acquired IPR&D asset
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed In Process Research And Development Asset
Business combination recognized identifiable assets acquired and liabilities assumed in process research and development asset.
Scenario [Domain]
Number of new programs
Number Of New Programs
Number of new programs.
2020 Plan [Member]
Two Thousand Twenty Plan [Member]
2020 Plan [Member]
Milestone events and royalties payment due upon specified regulatory milestone achievement
Milestone events and royalties payment due upon specified regulatory milestone achievement.
Milestone events and royalties payment due
Debt Securities, Available-for-Sale, Fair Value to Amortized Cost, after Allowance for Credit Loss [Abstract]
Common Stock, Value, Issued
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common stock, $0.001 par value; 300,000,000 shares authorized as of December 31, 2024, and December 31, 2023; 167,755,715 and 127,462,409 shares issued and outstanding as of December 31, 2024 and December 31, 2023, respectively
Assets, fair value
Cash and Cash Equivalents, Fair Value Disclosure
Development based milestone payments under agreement
Development Based Milestone Payments Under Agreement
Aggregate potential clinical development milestone payments available to be earned under a collaboration arrangement for each available target selected by the collaborator.
CARES Act, percentage of interest deducted by tax payers
C A R E S Act Percentage Of Interest Deducted By Tax Payers
CARES Act, percentage of interest deducted by tax payers.
Deferred tax assets capitalized research and development expense.
Deferred tax assets capitalized research and development expense
Capitalized R&D
Collaborative arrangement, purpose
Collaborative Arrangement, Nature and Purpose
Incremental stock compensation expense recognized in connection with acquisition
Stock-based compensation expense associated with accelerated vesting for certain stock options
Share-Based Payment Arrangement, Accelerated Cost
Contingent Consideration Type [Domain]
Present value of operating lease liabilities
Operating Lease, Liability
Total operating lease liabilities
Measurement Frequency
Measurement Frequency [Axis]
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses
Deferred Tax Assets, Operating Loss Carryforwards, Total
Net operating losses
Deferred Tax Assets, Operating Loss Carryforwards
Commitments and Contingencies
Commitments and contingencies (Note 11)
Offering Expenses
Offering expenses.
Offering expenses
Incremental charges
Share-Based Payment Arrangement, Plan Modification, Incremental Cost
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss
12 Months or Longer, Unrealized Losses
12 Months or Longer, Unrealized Losses
Significant Accounting Policies
Significant Accounting Policies [Text Block]
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Reportable Segment Revenue, Operating Expenses, and Net Loss
Precision Oncology And Genetic Diseases [Member]
Precision Oncology And Genetic Diseases [Member]
Precision Oncology And Genetic Diseases.
Research and development expenses
Research and Development Expense (Excluding Acquired in Process Cost)
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Contract asset
Increase (Decrease) in Commodity Contract Assets and Liabilities
Total lease payments
Lessee, Operating Lease, Liability, to be Paid
Cybersecurity Risk Management Third Party Engaged [Flag]
Performance-Based Stock Options [Member]
Performance-based stock options.
Accrued consulting and professional services.
Accrued Consulting and Professional Services
Consulting and professional services
Entity Small Business
Segment Reporting Information [Line Items]
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Net operating loss carryforwards, federal
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Earnout payments completion period
Earnout Payments Completion Period
Earnout payments completion period.
Total revenue
Revenues
U.S treasury bills [Member]
US Treasury Securities [Member]
U.S. treasury bills [Member]
Investments, Fair Value Disclosure, Total
Total investments
Investments, Fair Value Disclosure
Net acquired assets
Net acquired assets
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net
Market-Based Awards 2020 Stock Plan [Member]
Market-Based Awards two thousand twenty stock plan [Member]
Market-based awards two thousand twenty stock plan.
Credit Facility
Credit Facility [Axis]
Number Of New Discovery Stage Programs
Number of new discovery stage programs.
Number of discovery stage programs
Net amortization of premiums and discounts on investments
Accretion (Amortization) of Discounts and Premiums, Investments
Performance-Based R S Us.
Performance-Based RSUs [Member]
Performance-Based RSUs [Member]
Stock Compensation
Compensation Related Costs, Policy [Policy Text Block]
Cash flows from financing activities:
Net Cash Provided by (Used in) Financing Activities [Abstract]
Weighted Average Exercise Price Per Share, Outstanding Beginning Balance
Weighted Average Exercise Price Per Share, Outstanding Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Liabilities
Liabilities [Abstract]
Debt securities unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions
Asset Class [Axis]
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]
External Costs for Platform Technologies and Preclinical Programs
External costs for platform technologies and preclinical programs.
External costs for platform technologies and preclinical programs
State [Member]
State and Local Jurisdiction [Member]
Other
Accrued Other Expenses Current
Accrued other expenses current.
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Operating lease assets obtained in exchange for operating lease liabilities
Measurement Frequency
Measurement Frequency [Domain]
Genentech [Member]
Genentech Inc.
Genentech Inc. [Member]
Deferred Tax Assets, Valuation Allowance, Total
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
Weighted-average remaining lease term
Operating Lease, Weighted Average Remaining Lease Term
Subsequent Events
Subsequent Events [Text Block]
Tax Cuts and Jobs Act of 2017, maximum percentage of interest deducted by tax payers
Tax Cuts And Jobs Act Of2017 Maximum Percentage Of Interest Deducted By Tax Payers
Tax Cuts and Jobs Act of 2017, maximum percentage of interest deducted by tax payers.
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Fair value of market based awards
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grant Date Fair Value
Share based compensation arrangement by share based payment award equity instruments other than options grant date fair value.
Fair value of market based awards
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Grant Date Fair Value
Share based compensation arrangement by share based payment award options grants in period grant date fair value.
Depreciation and amortization
Deferred Tax Assets Depreciation And Amortization
Deferred tax assets depreciation and amortization.
Business combination contingent consideration arrangements change in amount of contingent milestone payments
Business combination contingent consideration arrangements change in amount of contingent milestone payments.
Change in fair value of Contingent Milestone Payments
President and Chief Executive Officer.
President and Chief Executive Officer [Member]