0001812364 2026-05-21 2026-05-21 0001812364 1 2026-05-21 2026-05-21 iso4217:USD pure shares S-3 424B5 EX-FILING FEES 333-281308 0001812364 Relay Therapeutics, Inc. N/A N/A S-3 Relay Therapeutics, Inc. false Equity Common Stock, $0.001 per share true 26354167 316250004.00 0.0001381 43674.13 316250004.00 43674.13 0.00 0.00 43674.13 (1) Calculated in accordance with Rule 457(r) under the Securities Act of 1933, as amended (the "Securities Act"). The fee payable in connection with the offering pursuant to this prospectus supplement has been paid in accordance with Rule 456(b) under the Securities Act, and represents deferred payment of the registration fees in connection with the registrant's Registration Statement on Form S-3ASR (Registration No. 333-281308). (2) Includes 3,437,500 shares of common stock that the underwriters have an option to purchase. 316250004.00 true