Entity Address, City or Town
Deferred tax liabilities
Deferred Tax Liabilities, Net [Abstract]
Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items]
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Summary of Reconciliation of Expected Income Tax (Benefit) Computed Using Federal Statutory Income Tax Rate to Effective Income Tax Rate
Fair Value Disclosures [Abstract]
Assets obtained in asset acquisition of ZebiAI
Fair Value of Assets Acquired
Earnings Per Share [Abstract]
Fair Value, Inputs, Level 1 [Member]
Level 1 [Member]
Schedule of Accrued Expenses
Schedule of Accrued Liabilities [Table Text Block]
Domestic Tax Authority [Member]
Federal [Member]
Issuance of common stock in follow-on offering, net
Stock Issued During Period, Value, New Issues
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities:
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Dividend yield
License Agreement Terms [Member]
License Agreement Terms [Member]
Amendment Flag
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value
Fair value of shares, vested
Additions of property and equipment in accounts payable and accrued expenses
Capital Expenditures Incurred but Not yet Paid
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Share-based Payment Award, Number of Shares Authorized
Subsequent Event Type [Domain]
Subsequent Event Type
Business Acquisition, Share Price
Average share value of 5-day
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table]
Operating Lease, Right-of-Use Asset
Operating lease assets
Right of use asset
Postemployment Benefits [Abstract]
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
Net operating loss carryforwards, state
Cowen.
Cowen [Member]
Summary of operating lease presentation in consolidated statements of operations and comprehensive loss.
Summary Of Operating Lease Presentation In Consolidated Statements Of Operations And Comprehensive Loss Table [Text Block]
Summary of Operating Lease Presentation in Consolidated Statements of Operations and Comprehensive Loss
Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration
Net operating loss carryforwards, not subject to expiration
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List]
Issuance of common stock in initial public offering/follow-on offering, net
Issuance of common stock in initial public offering, net
Issuance of common stock in initial public offering, net.
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: interest
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Common Share
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents
Statement [Table]
Statement [Table]
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Non-current operating lease liabilities
Proceeds from issuance of common stock in initial public offering, net
Proceeds From Issuance Initial Public Offering Net
Proceeds from issuance initial public offering net.
Issuance of common stock in follow-on offering, net
Stock Issued During Period Value Acquisition New Issues
Stock issued during period value acquisition new issues.
Operating Lease, Payments
Operating lease, payments
Fixed lease payments
Shares of common stock purchased
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Purchase of common stock under ESPP, shares
Liabilities assumed in asset acquisition of ZebiAI
Liabilities Assumed
Business Acquisition, Effective Date of Acquisition
Acquisition date
Number of Operating Segments
Number of operating segments
Common stock issued upon milestone achievement
Common stock issued upon milestone achievement.
Preferred Stock, Shares Outstanding
Preferred stock shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Business Acquisition [Axis]
Milestone payments.
Milestone Payments
Milestone payments
Auditor Firm ID
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Beginning Balance
Weighted Average Grant Date Fair Value, Ending Balance
Weighted Average Exercise Price Per Share, Unvested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Vested
Commitments and contingencies disclosure.
Commitments And Contingencies Disclosure [Table]
Commitments And Contingencies Disclosure [Table]
Time-based stock options.
Time-Based Stock Options [Member]
Deferred revenue
Increase (Decrease) in Deferred Revenue
Business Combination Disclosure [Text Block]
Acquisition of ZebiAI
Operating lease liabilities.
Operating Lease Liabilities [Member]
Operating lease liabilities
Income Tax Authority [Domain]
Income Tax Authority
Schedule of operating lease presentation in consolidated balance sheet.
Schedule Of Operating Lease Presentation In Consolidated Balance Sheet Table [Text Block]
Schedule of Operating Leases Presentation in Consolidated Balance Sheets
Deferred Tax Assets, Tax Credit Carryforwards
Tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Total
Product and Service [Axis]
Product and Service
Business Combination, Contingent Consideration, Liability, Total
Business Combination, Contingent Consideration, Liability
Beginning balance
Ending balance
Contingent consideration liability
Fair value of contingent milestone payments and earnout payments
Lessee, Operating Leases [Text Block]
Leases
CARES Act, description of corporate tax payers
C A R E S Act Description Of Corporate Tax Payers
CARES Act description of corporate tax payers.
Percentage of commission owed to sales agent under at-the-market offering
Percentage of commission owed to sales agent under at-the-market offering
Percentage of commission owed to sales agent under at-the-market offering.
Share-Based Payment Arrangement, Option [Member]
Stock Options [Member]
Options to purchase common stock [Member]
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining lease term
Liabilities and Equity
Total liabilities and stockholders' equity
Plan Name [Domain]
Plan Name
Other current liabilities
Other Liabilities, Current
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]
Change in fair value of contingent consideration liability
Change in fair value of contingent consideration liabilities
Amount of increase (decrease) in the fair value of contingent consideration recognized in the income statement.
Underwriting discounts, commissions and other offering expenses
Underwriting Discounts, Commissions And Other Offering Expenses
Underwriting discounts, commissions and other offering expenses.
Investments with maturity of one year or less.
Investments With Maturity Of One Year Or Less [Member]
Investments with a maturity of one year or less [Member]
CARES Act, percentage of bonus depreciation.
C A R E S Act Percentage Of Bonus Depreciation
CARES Act, percentage of bonus depreciation
Entity Incorporation, State or Country Code
Income Tax Examination, Description
Description of income tax examinations
Consulting And Management Services [Member]
Consulting And Management Services [Member]
Consulting And Management Services [Member]
Investments [Abstract]
Proceeds from Stock Plans
Proceeds from issuance of common stock under ESPP
Nonfinancial Liabilities Fair Value Disclosure
Total liabilities
Liabilities, Current
Total current liabilities
After-tax contributions
Stock Issued During Period, Value, Employee Stock Purchase Plan
Purchase of common stock under ESPP
2025
Lessee, Operating Lease, Liability, to be Paid, Year Three
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Business Acquisition, Acquiree [Domain]
Fair Value, Recurring [Member]
Fair value on a recurring basis [Member]
Income Tax, Policy [Policy Text Block]
Income Taxes
Milestone payment due upon specified regulatory milestone achievement.
Milestone Payment Due Upon Specified Regulatory Milestone Achievement
Milestone payment Due
Preferred Stock, Shares Authorized
Preferred stock shares authorized
Operating Lease, Weighted Average Discount Rate, Percent
Weighted-average discount rate
Compensation costs
Accrued Compensation Costs
Accrued compensation costs.
Investment Secondary Categorization [Axis]
Investment Secondary Categorization
Entity Small Business
Payment for upfront consideration
Payment For Upfront Consideration
Payment for upfront consideration.
Operating Leased Assets [Line Items]
Operating Leased Assets [Line Items]
Cash, cash equivalents, and restricted cash per statements of cash flows
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash, cash equivalents and restricted cash at end of period
Cash, cash equivalents and restricted cash at beginning of period
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Compensation Related Costs, Policy [Policy Text Block]
Stock-Based Compensation
Milestone payments.
Milestone Payments [Member]
Variable consideration related to reimbursements due for research and development services.
Variable Consideration Related To Reimbursements Due For Research And Development Services
Variable consideration related to reimbursements due for research and development services
Investments [Domain]
Investments
Research and development arrangement contract to perform for others renewal period.
Research And Development Arrangement Contract To Perform For Others Renewal Period
Agreement renewal period
Operating Income (Loss) [Member]
Operating Income (Loss) [Member]
Series C Preferred Stock [Member]
Series C Preferred Stock [Member]
Area of Land
Area of land
Assets, Current
Total current assets
Property, Plant and Equipment [Line Items]
Property Plant and Equipment [Line Items]
Issuance of common stock in initial public offering/follow-on offering, net, Shares
Issuance of Common Stock in Initial Public Offering Shares
Issuance of common stock in initial public offering shares.
Reclassification of restricted stock liability to additional paid in capital
Reclassification Of Restricted Stock Liability To Additional Paid In Capital
Reclassification of restricted stock liability to additional paid-in capital
Weighted average shares of common stock, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Convertible preferred stocks.
Convertible Preferred Stocks Member
Convertible preferred stock [Member]
City Area Code
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate Intrinsic Value, Outstanding Value
Business Description and Basis of Presentation [Text Block]
Nature of Business and Basis of Presentation
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Cancelled, Number of Shares
Share-Based Payment Arrangement [Abstract]
Deferred tax liabilities operating lease assets.
Deferred Tax Liabilities Operating Lease Assets
Operating lease assets
Unrealized holding loss
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment and Tax
Cash received for milestone payment
Cash Received for Milestone Payment
Cash received for milestone payment.
Accrued Expenses
Accrued Expenses [Text Block]
Accrued expenses text block.
Liabilities
Total liabilities
Document Period End Date
Restricted Stock [Member]
Restricted Stock [Member]
Unvested restricted stock [Member]
Investments with maturity of one to two years.
Investments With Maturity Of One To Two Years [Member]
Investments with a maturity of one to two years [Member]
Deferred tax assets operating loss carryforwards beginning to expire year.
Deferred Tax Assets Operating Loss Carryforwards Beginning To Expire Year
Net operating loss carryforwards, beginning to expiring year
Construction in Progress [Member]
Construction in Process [Member]
Increase in fair value of contingent milestone payments.
Increase in fair value of contingent milestone payments
Increase in fair value of Contingent Milestone Payments
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Stock-based compensation
In Process Research and Development, Policy [Policy Text Block]
Acquired In-Process Research and Development
Tax Cuts and Jobs Act of 2017, description of corporate tax payers.
Tax Cuts And Jobs Act Of2017 Description Of Corporate Tax Payers
Tax Cuts and Jobs Act of 2017, description of corporate tax payers
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value of stock option granted
Milestone payment receivable.
Milestone Payment Receivable
Milestone payment receivable
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Contract with Customer, Liability, Noncurrent
Contract liability
Statistical Measurement [Axis]
Statistical Measurement
Vesting of restricted common stock shares.
Vesting Of Restricted Common Stock Shares
Vesting of restricted common stock ,shares
Less than 12 Months, Fair Value
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Other current assets
Other Assets, Current
Interest Income, Other
Interest income
Related Party [Axis]
Related Party
Assets
Total assets
Contract with Customer, Asset, after Allowance for Credit Loss
Contract asset
Contract with Customer, Asset, after Allowance for Credit Loss, Total
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock upon initial public offering, shares
State and Local Jurisdiction [Member]
State [Member]
Schedule of Earnings Per Share, Basic, by Common Class, Including Two Class Method [Table]
Issuance of common stock upon milestone achievement,shares
Issuance of common stock upon milestone achievement, shares
Issuance of common stock upon milestone achievement, shares.
Non-refundable milestone for completion amount.
Non Refundable Milestone For Completion Amount
Non-refundable milestone payment for completion amount
Net loss attributable to common stockholders per share, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
EQRx Inc.
EQRx Inc Member
EQRx, Inc [Member]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Summary of Antidilutive Securities Excluded From Computation of Earnings Per Share
Number of common stock issued upon milestone achievement
Number of Common Stock Issued Upon Milestone Achievements
Number of common stock issued upon milestone achievements.
Patent costs.
Patent Costs Policy [Text Block]
Patent Costs
Entity Address, Postal Zip Code
BMR-Hampshire, LLC. [Member]
BMR-Hampshire, LLC. [Member]
BMR Hampshire, LLC [Member]
Other Liabilities [Member]
Other Liabilities [Member]
Increase decrease in operating lease assets and liabilities net.
Increase decrease in operating lease assets and liabilities net
Operating lease assets and liabilities, net
Stock issued during period additional shares issued.
Stock issued during period additional shares issued
Additional shares issued
DE shaw research.
D E Shaw Research [Member]
DE Shaw Research [Member]
Document Fiscal Period Focus
Restricted Cash
Restricted cash
Restricted Cash, Total
Conversion of preferred stock into common stock upon initial public offering
Stock issued during period value conversions of convertible securities
Stock issued during period value conversions of convertible securities
Increase (Decrease) in Accounts Receivable
Accounts receivable
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Deferred Tax Assets, Valuation Allowance, Total
Undesignated preferred stock, $0.001 par value, 10,000,000 shares authorized as of December 31, 2022 and December 31, 2021; no shares issued and outstanding at December 31, 2022 and December 31, 2021
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Milestone payment due for first three targets
Milestone Payment Due Upon Specified Regulatory Milestone Achievement for First Three Targets
Milestone payment due upon specified regulatory milestone achievement for first three targets.
Counterparty Name [Domain]
Counterparty Name
Total operating lease liabilities
Operating Lease, Liability
Present value of operating lease liabilities
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Percentage of additional common stock authorized.
Percentage Of Additional Common Stock Authorized
Percentage of additional common stock authorized
Net operating loss carryback period
CARES Act net operating loss carry back period.
Statement of Financial Position [Abstract]
Entity File Number
Securities Act File Number
Scenario [Domain]
Increase (Decrease) in Prepaid Expense
Prepaid expenses and other current assets
Statement of Cash Flows [Abstract]
License and transfer agreement.
License And Transfer Agreement [Member]
Transfer of License [Member]
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Thereafter
Contingent Milestone Payments
Business Combination, Contingent Milestone Payments
Business combination, contingent milestone payments.
Schedule of Investments [Abstract]
Retirement Benefits [Text Block]
Retirement Benefits
Geographical [Domain]
Geographical
Statistical Measurement [Domain]
Statistical Measurement
Statement of Stockholders' Equity [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Percentage of fair market value of common stock
Auditor Location
Other Current Liabilities [Member]
Class of Stock [Domain]
Class of Stock
Stockholders' Equity Note [Abstract]
Subsequent Events [Abstract]
Fair Value Measurements
Fair Value Disclosures [Text Block]
Schedule of Changes in Contingent Consideration Liability
Schedule of changes in fair value of contingent consideration liability.
Schedule Of Changes In Fair Value Of Contingent Consideration Liability [Table Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Life, Vested
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock upon exercise of stock options
Net proceeds
Zebi A I Therapeutics Inc [Member]
ZebiAI Therapeutics, Inc. [Member]
ZebiAI Therapeutics, Inc.
Deferred Tax Assets, Tax Credit Carryforwards, Research
Research and development tax credit carryforwards
Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Increase (Decrease) in Commodity Contract Assets and Liabilities
Contract asset
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment, Net
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
Summary Of The Restricted Stock Activity
Antidilutive Securities [Axis]
Related Party Transaction, Expenses from Transactions with Related Party
Related Party Expense
Preferred Stock, Par or Stated Value Per Share
Preferred stock par value
Contract with Customer, Liability, Current
Deferred revenue
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Unrealized Gains
Unrealized Losses
Credit Facility [Domain]
Credit Facility
Transfer of active pharmaceutical ingredients.
Transfer Of Active Pharmaceutical Ingredients [Member]
Transfer of Active Pharmaceutical Ingredients [Member]
Subsequent Events [Text Block]
Subsequent Events
Weighted average shares of common stock, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Due to Related Parties
Due To Related Parties
Due to Related Parties, Total
Description of new accounting pronouncements not yet adopted.
Description Of New Accounting Pronouncements Not Yet Adopted Policy [Text Block]
Recently Issued Accounting Pronouncements Not Yet Adopted
Cash Equivalents [Member]
Cash equivalents [Member]
Credit Facility [Axis]
Credit Facility
Computer Equipment [Member]
Computer Equipment [Member]
General and Administrative Expense [Member]
General and administrative expenses [Member]
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Milestones repayable (Note 11)
Milestones Repayable Current
Milestones repayable current.
Current Fiscal Year End Date
Investment Type [Axis]
Investment Type
Non-refundable upfront payment.
Non Refundable Upfront Payment
Non-refundable upfront payment
Depreciation
Depreciation expense
Depreciation, Total
Financial Instruments [Domain]
Financial Instruments
Entity Address, Address Line One
Purchase date
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, purchase date
Share-based compensation arrangement by share-based payment award, fair value assumptions, purchase date.
Document Annual Report
Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
Schedule of Estimated Fair Value of Employee Stock Purchase Plan
Supplemental disclosure of non-cash activities:
Supplemental Cash Flow Information [Abstract]
Investment, Policy [Policy Text Block]
Investments
Components of Deferred Tax Assets [Abstract]
Undesignated preferred stock.
Undesignatedpreferredstock [Member]
Undesignated Preferred Stock [Member]
Contingent Consideration Type [Domain]
Restricted Cash, Noncurrent
Restricted cash
Income Tax Expense (Benefit)
Income tax benefits
Income Tax Expense (Benefit), Total
399 Binney Street, Cambridge, Massachusetts.
Binney Street Cambridge Massachusetts [Member]
399 Binney Street [Member]
Income Tax Disclosure [Text Block]
Income Taxes
Preferred Stock, Shares Issued
Preferred stock shares issued
Preferred Stock, Shares Issued, Total
Balance Sheet Location [Domain]
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Revenue, Remaining Performance Obligation, Amount
Remaining performance obligations
Income Tax Disclosure [Abstract]
Restricted cash and cash equivalents at carrying value abstract.
Restricted Cash And Cash Equivalents At Carrying Value [Abstract]
Collaborative Arrangement [Member]
Collaboration and License Agreement [Member]
Issuance of common stock in follow-on offering, net, shares
Stock Issued During Period, Shares, New Issues
Common stock shares sold
Potential development milestone payments.
Potential Development Milestone Payments
Potential development milestone payments
Significant accounting policies.
Significant Accounting Policies [Line Items]
Significant Accounting Policies [Line Items]
Outstanding convertible preferred stock converted into common shares
Common stock shares issued upon conversion
Common stock shares issued upon conversion.
Extinguisment upon modification of Series C Preferred Stock (Note 9)
Loss on extinguishment and reissuance of preferred stock.
Loss On Extinguishment And Reissuance Of Preferred Stock
Assets, Fair Value Disclosure [Abstract]
Assets
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Research and manufacturing contracts.
Research And Manufacturing Contracts Policy [Text Block]
Research and Manufacturing Contracts
Conversion of Stock, Amount Converted
Conversion of preferred stock into common stock upon initial public offering
Auditor Name
CARES Act, percentage of corporate charitable deduction limit.
C A R E S Act Percentage Of Corporate Charitable Deduction Limit
CARES Act, percentage of corporate charitable deduction limit
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Cancelled
Operating Income (Loss)
Loss from operations
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance
Shares, Unvested
Related Party [Domain]
Related Party
Payments to Acquire Businesses, Net of Cash Acquired, Total
Payments to Acquire Businesses, Net of Cash Acquired
Cash paid for acquisition of ZebiAI, net of cash acquired
Cash paid for acquisition of ZebiAI, net of cash acquired
Scenario [Axis]
Number of discovery stage programs.
Number of discovery stage programs
Issuance of common stock upon milestone achievement
Issuance of common stock upon milestone achievement
Issuance of common stock upon milestone achievement.
Weighted average shares of common stock, diluted
Weighted Average Number Of Shares Outstanding Diluted
Weighted average number of shares outstanding diluted.
Aggregate Intrinsic Value, Unvested Value
Sharebased Compensation Arrangement by Sharebased Payments Award Options Non Vested Intrinsic Value 1
Research and Development in Process
In-process research and development expenses
Total, Fair Value
Total, Fair Value
Debt Securities, Available-for-Sale, Unrealized Loss Position
Common Stock, Voting Rights
Common Stock, Voting Rights
Entity Filer Category
Share based compensation arrangement by share based payment award options non vested weighted average remaining contractual term.
Share Based Compensation Arrangement By Share Based Payment Award Options Non Vested Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Life, Unvested
Operating Expenses
Total operating expenses
Entity Current Reporting Status
Asset Class [Domain]
Asset Class
ICFR Auditor Attestation Flag
Research and development arrangement, annual fee.
Research And Development Arrangement Annual Fee
Research and development arrangement, annual fee
Investment [Text Block]
Investments
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate Intrinsic Value, Vested Value
Cash and cash equivalents fair value disclosure.
Cash And Cash Equivalents Fair Value Disclosure [Abstract]
Cash equivalents:
Stockholders' Equity Note Disclosure [Text Block]
Common Stock
Increase in deferred tax assets valuation allowance.
Increase In Deferred Tax Assets Valuation Allowance
Increase in valuation allowance
Business Combinations [Abstract]
Finite-Lived Intangible Assets, Net, Total
Finite-Lived Intangible Assets, Net, Beginning Balance
Finite-Lived Intangible Assets, Net, Ending Balance
Finite-Lived Intangible Assets, Net
Intangible asset
Stockholders' Equity Attributable to Parent
Ending balance
Beginning balance
Total stockholders' equity
Total, Unrealized Losses
Total, Unrealized Losses
Total, Unrealized Losses
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss
Operating lease assets.
Operating Lease Assets [Member]
Operating lease assets
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Asset Class [Axis]
Asset Class
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]
Summary of Fair Value of Available-for-Sale Investments by Type of Security
Entity Tax Identification Number
Income Statement Location [Axis]
Income Statement Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of Shares Underlying RSUs, Cancelled
Cancelled
Number of Shares Underlying RSUs, Cancelled
Common stock, $0.001 par value; 300,000,000 and 150,000,000 shares authorized at December 31, 2022 and December 31, 2021, respectively; 121,112,234 and 108,210,318 shares issued and outstanding at December 31, 2022 and December31, 2021, respectively
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Equity Components [Axis]
Equity Components
ZebiAI [Member]
ZebiAI.
Business Combination, Acquisition Related Costs
Acquisition-related costs
Lease expiration month and year.
Lease Expiration Month And Year
Operating lease agreement expiration date
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash Equivalents
Prepaid balance
Prepaid expenses
Prepaid Expense, Current, Total
Prepaid Expense, Current
Deferred tax assets lease liability.
Deferred Tax Assets Lease Liability
Lease liability
Leases [Abstract]
Concentration of credit risk and significant suppliers.
Concentration Of Credit Risk And Significant Suppliers Policy [Text Block]
Concentration of Credit Risk and Significant Suppliers
Entity Emerging Growth Company
Related Party Transaction [Axis]
Related Party Transaction
12 Months or Longer, Unrealized Losses
12 Months or Longer, Unrealized Losses
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss
Schedule of Business Acquisitions, by Acquisition [Table]
Operating Expenses [Abstract]
Operating expenses:
Vesting of restricted stock units, Shares
Vesting of restricted stock units, Shares.
Research and development arrangement, term of contract.
Research And Development Arrangement Term Of Contract
Research and development arrangement, term of contract
Collaboration and license arrangement.
Collaboration And License Arrangement [Line Items]
Collaboration And License Arrangement [Line Items]
Revenue [Policy Text Block]
Revenue Recognition
Business combination contingent consideration liability milestones payments measured.
Business combination contingent consideration liability milestones payments measured
Business combination contingent consideration liability, milestones payments measured
Letter of Credit [Member]
Letter of Credit [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Payments to Acquire Investments
Purchases of investments
Payments to Acquire Investments, Total
Debt Securities, Available-for-Sale [Table]
Debt Securities Available For Sale [Table]
Entity Voluntary Filers
Vesting of restricted common stock value.
Vesting Of Restricted Common Stock Value
Vesting of restricted common stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility rate maximum
Retirement Benefits [Abstract]
Net loss attributable to common stockholders
Net loss attributable to common stockholders
Net Income Loss Available To Common Stockholders
Net income loss available to common stockholders.
Document Transition Report
Stand-alone selling prices.
Stand Alone Selling Prices [Member]
Stand-alone Selling Prices ("SSP") [Member]
Total accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Accrued Expenses And Other Current Liabilities
Accrued expenses and other current liabilities.
External research and development costs
Accrued external research and development expense current.
Accrued External Research And Development Expense Current
Assets, Fair Value Disclosure
Total assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Granted
Impairment, Long-Lived Asset, Held-for-Use
Impairment loss of long lived assets
Impairment, Long-Lived Asset, Held-for-Use, Total
Third Rock Venture [Member]
Third Rock Venture [Member]
Third Rock Venture [Member]
Basis of presentation.
Basis Of Presentation Policy [Text Block]
Basis of presentation
Sale of Stock, Price Per Share
Offering price per share
Collaboration and License Agreement with Genentech, Inc.
Collaborative Arrangement Disclosure [Text Block]
Sales Agreement [Member]
Sales agreement.
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Exercised
Accumulated other comprehensive loss
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Percent
Stock-based compensation
Unrealized loss on investments
Debt Securities, Available-for-Sale, Unrealized Gain (Loss)
Debt Securities, Available-for-Sale, Unrealized Gain (Loss), Total
Entity Common Stock, Shares Outstanding
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List]
Total other comprehensive loss
Other Comprehensive Income (Loss), Net of Tax
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Extinguishment upon modification of Series C Preferred Stock (Note 9)
Dividend upon extinguishment of Series C Preferred Stock (Note 9)
Dividend upon extinguishment of Series preferred stock
Dividend upon extinguishment of Series preferred stock.
Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions
Debt securities unrealized loss position
Operating lease liabilities
Operating Lease, Liability, Current
Operating lease liabilities, current
Land Subject to Ground Leases
Land subject to ground leases
Variable Interest Entity, Initial Consolidation, Gain (Loss)
Loss on initial consolidation of variable interest entity
Loss on initial consolidation of variable interest entity
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Summary of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis and Level of the Fair Value Hierarchy
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Dividend upon extinguishment of Series C Preferred Stock
Dividend upon extinguishment of Series C Preferred Stock (Note 9)
Extinguisment upon modification of Series C Preferred Stock (Note 9)
Dividend upon extinguishment of preferred stock.
Fair value of common stock issued in asset acquisition of ZebiAI
Stock Issued
Payment, Tax Withholding, Share-Based Payment Arrangement
Amount withheld from employees, on an after-tax basis
Employee stock purchase plan.
Employee Stock Purchase Plan [Member]
ESPP [Member]
Collaborative Arrangement, Nature and Purpose
Collaborative arrangement, purpose
Deferred Tax Assets, Operating Loss Carryforwards
Net operating losses
Deferred Tax Assets, Operating Loss Carryforwards, Total
Cash and cash equivalents maturity date description.
Cash And Cash Equivalents Maturity Date Description
Maturity days for highly liquid investments
Entity Registrant Name
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Earnings Per Share [Text Block]
Net Loss Per Share
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Estimated Fair Value of Stock Options
Class of Stock [Axis]
Class of Stock
U.S. agency securities [Member]
US Government Agencies Debt Securities [Member]
U.S agency securities [Member]
Debt Instrument, Maturity Date
Letter of credit expiry date
Letter of credit expiration date
Revenues
Total revenue
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Research and development services.
Research And Development Services [Member]
Research and Development Services [Member]
Property, Plant and Equipment, Net
Property and equipment, net
Total property and equipment, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Award Type [Domain]
Award Type
Statement [Line Items]
Statement [Line Items]
CARES Act, percentage of eliminates of taxable income.
C A R E S Act Percentage Of Eliminates Of Taxable Income
CARES Act, percentage of eliminates of taxable income
Title of 12(b) Security
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Common Stock [Member]
Common Stock [Member]
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Restricted shares.
Restricted shares [member]
Restricted Shares [Member]
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows from operating activities:
Equity Component [Domain]
Equity Component
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Incremental share-based compensation expense recognized in connection with acquisition
Share-Based Payment Arrangement, Accelerated Cost
Stock-based compensation expense associated with accelerated vesting for certain stock options
Convertible Preferred Stock [Member]
Convertible Preferred Stock [Member]
Business combination contingent consideration arrangements change in amount of contingent earnout payments.
Business combination contingent consideration arrangements change in amount of contingent earnout payments
Contingent Earnout Payments related to acquisition of ZebiAI
License and other revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Collaboration revenue
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Entity Address, State or Province
2026
Lessee, Operating Lease, Liability, to be Paid, Year Four
Geographical [Axis]
Geographical
Net (decrease) increase in cash, cash equivalents, and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Document Type
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Net operating loss carryforwards, federal
Non-refundable milestone transfer amount.
Non Refundable Milestone Transfer Amount
Non-refundable milestone payment transfer amount
Payment related to collaboration or other agreements.
Payment Related To Collaboration Or Other Agreements
Payment related to collaboration or other agreements
Contribution toward the cost of construction and tenant improvements for the premises.
Contribution toward the cost of construction and tenant improvements for the premises
Contribution toward the cost of construction and tenant improvements for the premises
Entity Shell Company
Share-Based Payment Arrangement, Expense
Total share-based compensation expense
Stock-based compensation expense
Laboratory equipment.
Laboratory Equipment [Member]
Laboratory Equipment [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Income tax disclosure.
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Security Exchange Name
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Significant Accounting Policies [Text Block]
Significant Accounting Policies
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Total unrecognized compensation cost related to the unvested stock-based awards, Weighted average period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Life, Outstanding
Collaboration agreement transaction price.
Collaboration Agreement Transaction Price
Collaboration agreement transaction price
Other comprehensive loss:
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Percentage of payment related to collaboration or other agreements.
Percentage Of Payment Related To Collaboration Or Other Agreements
Percentage of payment related to collaboration or other agreements
Operating Lease, Cost
Operating lease costs
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units [Member]
Unvested restricted stock units [Member]
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Summary of Future Minimum Lease Payments
Tabular disclosure of reserved shares of common stock for future issuance.
Reserved Shares Of Common Stock For Future Issuance Table Table [Text Block]
Summary of Reserved Shares of Common Stock
Aggregate fair value consideration transferred
Business combination consideration transferred equity interests issued
Business combination consideration transferred equity interests issued.
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets, Total
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets
Assets obtained in asset acquisition
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Schedule of Restricted Stock Units Activity
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles
Intangible asset
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Schedule of Stock Option Activity
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted Accounting Pronouncements
Common Stock, Shares, Outstanding
Common stock shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Proceeds from issuance of common stock upon exercise of stock options
Proceeds From Issuance Of Common Stock Upon Exercise Of Stock Options
Proceeds from issuance of common stock upon exercise of stock options.
Business Acquisition [Line Items]
Accretion (Amortization) of Discounts and Premiums, Investments
Net amortization of premiums and discounts on investments
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
R&D credit carryovers
Fair Value, Inputs, Level 2 [Member]
Level 2 [Member]
Lease Agreement [Member]
Lease Agreement [Member]
Lease Agreement
Debt Securities, Available-for-Sale
Fair Value
Debt Securities, Available-for-sale, Total
Net Cash Provided by (Used in) Investing Activities [Abstract]
Cash flows from investing activities:
Investments
Investments
Investments, Total
Precision Oncology and Genetic Disease Indications [Member]
Precision Oncology And Genetic Disease Indications [Member]
precision oncology and genetic disease indications.
Commitments and contingencies (Note 12)
Commitments and Contingencies
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net
Net acquired assets
Net acquired assets
Common Stock, Shares, Issued
Common stock shares issued
Common Stock, Shares, Issued, Total
Liabilities [Abstract]
Liabilities
U.S. treasury bills [Member]
US Treasury Securities [Member]
U.S treasury bills [Member]
Debt Securities, Available-for-Sale, Unrealized Loss Position [Abstract]
Minimum [Member]
Minimum [Member]
Operating lease liabilities net of current portion.
Operating Lease Liabilities Net Of Current Portion [Member]
Operating lease liabilities, net of current portion
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate maximum
Lessee, Leases [Policy Text Block]
Lease Agreements
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Vested
Total accrued expenses
Accrued Liabilities, Current
Accrued expenses and other current liabilities
Accrued expenses
Weighted Average Exercise Price Per Share, Unvested
Weighted Average Exercise Price Per Share, Unvested
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price, Beginning Balance
Business Combination, Description [Abstract]
Stockholders' equity:
Stockholders' Equity Attributable to Parent [Abstract]
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State taxes, net of federal benefit
CARES Act, Period of qualified improvement property for cost-recovery.
C A R E S Act Period Of Qualified Improvement Property For Cost Recovery
CARES Act, period of qualified improvement property for cost-recovery
Counterparty Name [Axis]
Counterparty Name
Entity Address, Address Line Two
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents
Revenues [Abstract]
Revenue:
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Cancelled
Award Type [Axis]
Award Type
Subsequent Event [Member]
Subsequent Event [Member]
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Total unrecognized compensation cost related to the unvested stock-based awards, Value
Aggregate potential regulatory milestone payments available to be earned under a collaboration arrangement.
Regulatory Based Milestone Payments Under Agreement
Regulatory based milestone payments under agreement
Business Combination, Consideration Transferred, Total
Business Combination, Consideration Transferred
Consideration transferred
Related Party Transaction [Domain]
Related Party Transaction
Total gross deferred tax assets
Deferred Tax Assets, Gross
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Total intrinsic value
Other Nonoperating Income (Expense)
Total other income, net
Schedule of Total Stock-based Compensation Expense Recognized
Schedule of compensation cost for share based payment arrangements allocation of share based compensation costs [Table Text Block]
Schedule of compensation cost for share based payment arrangements allocation of share based compensation costs.
Research and Development Expense
Research and development expenses
Research and development expense
Research and Development Expense, Total
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Lessee, Operating Lease, Term of Contract
Term of the lease
Acquired research and development in process.
Acquired research and development in process
Acquired in-process research and development
Average stock price upon milestone settlement
Average stock price upon milestone settlement
Average stock price upon milestone settlement.
Other income (expense).
Other Income Expense
Other income (expense)
60 Hampshire Street [Member]
Hampshire Street, Cambridge, Massachusetts [Member]
Hampshire street, Cambridge, Massachusetts> [Member]
Deferred Tax Assets, Goodwill and Intangible Assets
Intangibles
Entity Central Index Key
Other income:
Other Income and Expenses [Abstract]
Lessee, Operating Lease, Existence of Option to Terminate [true false]
Operating lease option to terminate
Nature of business and basis of presentation.
Nature Of Business And Basis Of Presentation [Line Items]
Nature of Business and Basis of Presentation [Line Items]
Accounting Policies [Abstract]
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Volatility
Expected volatility
Number of milestone targets.
Number Of Milestone Targets
Number of milestone targets
Maximum additional amount received upon milestone achievement.
Maximum Additional Amount Received Upon Milestone Achievement
Maximum additional amount received upon milestone achievement
Fair value of Contingent Milestone Payments upon acquisition
Fair value of Contingent Milestone Payments upon acquisition
Fair value of Contingent Milestone Payments upon acquisition.
HR+/HER2- Breast Cancer [Member]
H R H E R 2 Breast Cancer [Member]
HR+/HER2- breast cancer.
Measurement Frequency [Axis]
Measurement Frequency
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration
Net operating loss carryforwards, subject to expiration
Share-Based Payment Arrangement [Text Block]
Stock Compensation
General and Administrative Expense
General and administrative expenses
General and Administrative Expense, Total
Change in fair value of Contingent Milestone Payments
Business Combination, Contingent Consideration Arrangements, Change in Amount of Contingent Consideration, Liability
Change in fair value of contingent consideration liability
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Outstanding Ending Balance
Weighted Average Exercise Price Per Share, Outstanding Beginning Balance
Business Combination, Contingent Consideration Arrangements, Description
Contingent consideration payment description
Research and Development Expense [Member]
Research and development expenses [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate minimum
Proceeds from Sale and Maturity of Other Investments
Proceeds from maturities of investments
Proceeds from Sale and Maturity of Other Investments, Total
Forecast [Member]
Forecast [Member]
Operating lease assets obtained in exchange for operating lease liabilities
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Accrued professional services current.
Accrued Professional Services Current
Professional services
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Schedule of Held-to-Maturity Securities [Line Items]
Schedule Of Held To Maturity Securities [Line Items]
Investments by Secondary Categorization [Domain]
Investments by Secondary Categorization
Retained Earnings [Member]
Accumulated Deficit [Member]
Collaborative Arrangement, Rights and Obligations
Collaborative arrangement, rights and obligations
Business Acquisition, Equity Interest Issued or Issuable, Number of Shares
Issued shares of common stock
Money Market Funds [Member]
Money market funds [Member]
Effective Income Tax Rate Reconciliation, Percent
Total
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]
Significant accounting policies.
Significant Accounting Policies [Table]
Significant Accounting Policies [Table]
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Property, Plant and Equipment, Gross
Property and equipment
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Additional Paid in Capital
Additional paid-in capital
Additional Paid in Capital, Total
Additional Paid in Capital, Beginning Balance
Additional Paid in Capital, Ending Balance
Accounts Receivable, after Allowance for Credit Loss
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Total
Entity Interactive Data Current
Entity Public Float
Related Party Transactions Disclosure [Text Block]
Related Party Transactions
Letters of Credit Outstanding, Amount
Letter of credit
Effective income tax rate reconciliation permanent differences.
Effective Income Tax Rate Reconciliation Permanent Differences
Permanent differences
Related Party Transactions [Abstract]
2023
Lessee, Operating Lease, Liability, to be Paid, Year One
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Debt Securities, Available-for-Sale, Fair Value to Amortized Cost, after Allowance for Credit Loss [Abstract]
12 Months or Longer, Fair Value
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Debt securities in continuous unrealized loss position for more than 12 months
Local Phone Number
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Income tax computed at federal statutory rate
Unrecognized Tax Benefits
Unrecognized tax benefits
Unrecognized Tax Benefits, Beginning Balance
Unrecognized Tax Benefits, Ending Balance
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
Summary of Net Assets Acquired Based on Estimated Fair Values
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Summary of Computation of Basic and Diluted Net Loss Per Share
Common stock restriction period
Common stock, restriction period.
Common Stock Restriction Period
Laboratory and computer equipment.
Laboratory And Computer Equipment [Member]
Laboratory and Computer Equipment [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Other third parties [member].
Otherthird Parties [Member]
Other Third Parties [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Shares, Vested
Proceeds from Issuance of Convertible Preferred Stock
Proceeds from issuance of convertible preferred stock, net of issuance costs
Business combination contingent consideration liability, contingent earnout payments.
Business combination contingent consideration liability, contingent earnout payments
Business combination contingent consideration liability, contingent earnout payments
Contingent Earnout Payments
Lessee, Operating Lease, Existence of Option to Extend [true false]
Operating lease option to extent
Number of stock options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted, Number of Shares
Genentech agreement.
Genentech Agreement [Member]
Genentech Agreement [Member]
Other Liabilities, Noncurrent, Total
Other Liabilities, Noncurrent
Other liabilities
Income Statement Location [Domain]
Income Statement Location
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities, Total
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities
Liabilities assumed in asset acquisition
Liabilities assumed in asset acquisition
Property, Plant and Equipment [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Shares - Ending
Shares - Beginning
Shares, Outstanding
Ending balance, shares
Beginning balance, shares
Earnout payments.
Earnout Payments [Member]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Research and development arrangement, expiration date.
Research And Development Arrangement Expiration Date
Research and development arrangement, expiration date
Text Block [Abstract]
Effective income tax rate reconciliation in process research and development asset.
Effective Income Tax Rate Reconciliation In Process Research And Development Asset
IPR&D
IPR&D
Contingent Consideration by Type [Axis]
Collaboration and license arrangement.
Collaboration And License Arrangement [Table]
Collaboration And License Arrangement [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Options and Warrants Outstanding, Number of Shares Ending Balance
Options and Warrants Outstanding, Number of Shares Beginning Balance
Document Fiscal Year Focus
Investments in and Advances to Affiliates, Balance, Shares
Shares held
2024
Lessee, Operating Lease, Liability, to be Paid, Year Two
Increase in common stock capital shares reserved for future issuance.
Increase in Common Stock Capital Shares Reserved For Future Issuance
Increase in number of shares of common stock available for issuance
Net loss attributable to common stockholders per share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Assets [Abstract]
Assets
Increase (Decrease) in Accrued Liabilities
Accrued expenses and other liabilities
Increase (Decrease) in Accrued Liabilities, Total
Investments, Fair Value Disclosure
Total investments
Investments, Fair Value Disclosure, Total
Deferred Tax Assets, Net
Net deferred tax assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility rate minimum
Prepaid expense and other current asset balances
Prepaid Expense and Other Assets, Current
Commitments Disclosure [Text Block]
Commitments and Contingencies
Investments, Fair Value Disclosure [Abstract]
Investments:
Series A Preferred Stock [Member]
Series A Preferred Stock [Member]
Financial Instrument [Axis]
Financial Instrument
Milestone payment due for each target after first three target
Milestone Payment Due Upon Specified Regulatory Milestone Achievement For Each Target After First Three
Milestone payment due upon specified regulatory milestone achievement for each target after first three.
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Schedule of Operating Leased Assets [Table]
Schedule Of Operating Leased Assets [Table]
Liabilities and Equity [Abstract]
Liabilities and Stockholders' Equity
Nature of business and basis of presentation.
Nature Of Business And Basis Of Presentation [Table]
Nature Of Business And Basis Of Presentation [Table]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Antidilutive Securities, Name [Domain]
Income Tax Authority [Axis]
Income Tax Authority
Investments [Member]
Investments [Member]
Net deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Preferred Stock [Member]
Proceeds from issuance of common stock in follow-on offering, net
Proceeds from issuance of common stock upon follow-on offering, net.
Proceeds from issuance of common stock upon follow-on offering, net
Assets, Current [Abstract]
Current assets:
Dividends, Common Stock
Dividends declared
Dividends, Common Stock, Total
Collaboration and license arrangement.
Collaboration And License Arrangement [Abstract]
Commitments and contingencies disclosure.
Commitments And Contingencies Disclosure [Line Items]
Commitments and Contingencies Disclosure [Line Items]
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Summary of Deferred Tax Assets and Liabilities
Less than 12 Months, Unrealized Losses
Less than 12 Months, Unrealized Losses
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Available-for-sale Debt Securities in an Unrealized Loss Position
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Number of shares would be issued upon milestone achievement.
Number of Shares Would Be Issued Upon Milestone Achievement
Number of shares that would be issued upon milestone achievement
Defined Contribution Plan, Employer Discretionary Contribution Amount
Employer matching contribution
Payables and Accruals [Abstract]
Business combination recognized identifiable assets acquired and liabilities assumed assets loss on initial consolidation of variable interest entity.
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed Assets Loss On Initial Consolidation Of Variable Interest Entity
Loss on initial consolidation of VIE
Loss on initial consolidation of VIE
2016 Plan [Member]
Two Thousand Sixteen Plan [Member]
Two Thousand Sixteen Plan
2016 Plan [Member]
Measurement Frequency [Domain]
Measurement Frequency
CARES Act, maximum percentage of interest deducted by tax payers
C A R E S Act Maximum Percentage Of Interest Deducted By Tax Payers
CARES Act maximum percentage of interest deducted by tax payers.
Business combination recognized identifiable assets acquired and liabilities assumed in process research and development asset.
Business Combination Recognized Identifiable Assets Acquired And Liabilities Assumed In Process Research And Development Asset
Acquired IPR&D asset
Increase (Decrease) in Operating Capital [Abstract]
Changes in assets and liabilities:
Sale of Stock, Consideration Received Per Transaction
Aggregate gross proceeds from the sale of shares
2020 Plan [Member]
Two Thousand Twenty Plan [Member]
2020 Plan [Member]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Cover [Abstract]
Product and Service [Domain]
Product and Service
2027
Lessee, Operating Lease, Liability, to be Paid, Year Five
Preferred Stock, Convertible, Conversion Price
Preferred Stock Convertible Conversion Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Shares - Vested
Number of Shares Underlying RSUs, Vested
Number of Shares Underlying RSUs, Vested
Aggregate potential clinical development milestone payments available to be earned under a collaboration arrangement for each available target selected by the collaborator.
Development Based Milestone Payments Under Agreement
Development based milestone payments under agreement
CARES Act, percentage of interest deducted by tax payers.
C A R E S Act Percentage Of Interest Deducted By Tax Payers
CARES Act, percentage of interest deducted by tax payers
Capitalized R&D
Deferred tax assets capitalized research and development expense
Deferred tax assets capitalized research and development expense.
Liabilities, Current [Abstract]
Current liabilities:
Maximum [Member]
Maximum [Member]
Net cash (used in) provided by investing activities
Net Cash Provided by (Used in) Investing Activities
Furniture and Fixtures [Member]
Furniture and Fixtures [Member]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Issuance of common stock upon exercise of stock options, shares
Exercised, Number of Shares
Fair Value, Inputs, Level 3 [Member]
Level 3 [Member]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Total deferred tax liabilities
Deferred Tax Liabilities, Gross
Deferred Tax Liabilities, Gross, Total
Performance-based stock options.
Performance-Based Stock Options [Member]
Consulting and professional services
Accrued Consulting and Professional Services
Accrued consulting and professional services.
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock upon exercise of stock options
Segment Reporting, Policy [Policy Text Block]
Segment Information
Operations and Comprehensive Loss Statement [Abstract].
Operations And Comprehensive Loss Statement [Abstract]
Property, Plant and Equipment, Useful Life
Property and equipment, useful life
Foreign Tax Authority [Member]
Outside US [Member]
Deferred Tax Assets, Net [Abstract]
Deferred tax assets:
Common Stock, Shares Authorized
Common stock shares authorized
Trading Symbol
Subsequent Event Type [Axis]
Subsequent Event Type
Deferred Tax Assets, Other
Other
Business combination contingent consideration liability, milestones payments.
Business Combination Contingent Consideration Liability Milestones Payments
Business combination contingent consideration liability, milestones payments
Contingent Milestone Payments
Balance Sheet Location [Axis]
Milestone payment received.
Milestone payment received
Milestone payment received
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Total comprehensive loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Proceeds from Sale of Property, Plant, and Equipment
Proceeds from sale of equipment
Proceeds from Sale of Property, Plant, and Equipment, Total
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Unrealized Losses
Unrealized Losses
Increase (Decrease) in Other Operating Assets
Other assets
Increase (Decrease) in Other Operating Assets, Total
Plan Name [Axis]
Plan Name
Schedule of Related Party Transactions, by Related Party [Table]
Schedule Of Related Party Transactions By Related Party [Table]
Accrued other expenses current.
Accrued Other Expenses Current
Other
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Collaborative Arrangement, Accounting Policy [Policy Text Block]
Collaboration Agreements
Deferred tax assets tax credit carryforwards research expiration year.
Deferred Tax Assets Tax Credit Carryforwards Research Expiration Year
Research and development tax credit carryforwards, expiration year
Genentech Inc.
Genentech Inc [Member]
Genentech [Member]
Common Stock, Par or Stated Value Per Share
Common stock par value
Entity Well-known Seasoned Issuer
Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property
Loss on sale of equipment
Loss on sale of equipment
Stock Issued During Period, Shares, Acquisitions
Shares issued in connection with acquisition, shares
Income Tax Examination, Likelihood of Unfavorable Settlement
Description of Income tax benefit, likelihood of realized upon ultimate settlement
Tax Cuts and Jobs Act of 2017, maximum percentage of interest deducted by tax payers.
Tax Cuts And Jobs Act Of2017 Maximum Percentage Of Interest Deducted By Tax Payers
Tax Cuts and Jobs Act of 2017, maximum percentage of interest deducted by tax payers
Stock Issued During Period, Value, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock upon initial public offering
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of Shares Underlying RSUs, Granted
Stock Issued During Period, Value, Acquisitions
Shares issued in connection with acquisition of ZebiAI
Property and Equipment
Property, Plant and Equipment Disclosure [Text Block]
Research and Development Expense (Excluding Acquired in Process Cost)
Research and development expenses
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted Average Exercise Price Per Share, Granted
Deferred tax assets depreciation and amortization.
Deferred Tax Assets Depreciation And Amortization
Depreciation and amortization
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Shares authorized additionally under ESPP
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Anti-dilutive effect
Cash and Cash Equivalents, Fair Value Disclosure
Assets, fair value
Business combination contingent consideration arrangements change in amount of contingent milestone payments.
Business combination contingent consideration arrangements change in amount of contingent milestone payments
Contingent Milestone Payments related to acquisition of ZebiAI